Evidence map›Paper›PMID 40308917›Full record

ArticleFrontiers in public health2025

Chemicals of concern in select packaged hair relaxers available on the Kenyan market: an examination of ingredient labels and measurement of pH.

Beatrice N Irungu, Adana A M Llanos, Mary Nyangi, Teresa Olisa, Esther Matu, Amber Rockson, Alexis Schaefer, Adiba Ashrafi, Mary Beth Terry, Jasmine A McDonald and 5 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Beatrice N Irungu *Center for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Nairobi, Kenya.
Adana A M Llanos *Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, United States.
Mary NyangiCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Nairobi, Kenya.
Teresa OlisaCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Nairobi, Kenya.
Esther MatuAfrican-Caribbean Cancer Consortium (AC3), Philadelphia, PA, United States.
Amber RocksonDepartment of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, United States.
Alexis SchaeferDepartment of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, United States.
Adiba AshrafiDepartment of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, United States.
Mary Beth TerryDepartment of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, United States.
Jasmine A McDonaldDepartment of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, United States.
Janet NudelmanCampaign for Safe Cosmetics, Breast Cancer Prevention Partners, San Francisco, CA, United States.
Laura Dobbs GillanCampaign for Safe Cosmetics, Breast Cancer Prevention Partners, San Francisco, CA, United States.
Pujeeta ChowdharyCampaign for Safe Cosmetics, Breast Cancer Prevention Partners, San Francisco, CA, United States.
Sabina WachiraCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Nairobi, Kenya.
Cecilia KimaniCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Nairobi, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is an emerging interest in the investigation of hair relaxers as important sources of exposure to chemicals of concern (CoCs) and their associated adverse health effects. We focused on documentation of CoCs by examining labels of selected relaxers currently available on the market in Nakuru and Embu Counties, Kenya and measured the pH profiles to ensure compliance with Kenya Bureau of Standards. Methods: We enrolled 746 women aged 15-50 years in a cross-sectional study, which ascertained participants' sociodemographic characteristics, personal care products use in the last 7-14 days and ever use of hair dyes and chemical relaxers including the brand names of products used. Based on participants' questionnaire responses and product availability at beauty shops and supermarkets, we purchased 22 different relaxer products. The label of each product was reviewed and we recorded relaxer strength, manufacturer and location, listed ingredients, and other claims. To identify CoCs, we cross-checked the list of ingredients against the Campaign for Safe Cosmetics' (CSC) Red List and European Union's prohibited and restricted substances (Annex II and III respectively), Regulation 1223/2009 on cosmetics. The pH profiles of each product were determined using a benchtop pH meter. Results: Twenty-seven CoCs were documented upon examination with each relaxer listing more than one CoC. Thirteen out of 27 (48.2%) were fragrance chemicals with d-limonene/limonene and linalool, each being listed as an ingredient in 9 products. Fourteen (63.6%) relaxers had undisclosed ingredients listed as 'fragrance' and/or 'parfum'. Six of the identified CoCs are classified as Tier 1 (Do not use for everyone) per CSC Red List while 14.8% (4) are prohibited and 55.6% (15) are restricted substances per EU regulations. The pH values of the relaxers were within Kenya Bureau of Standards required range of 11-13. Conclusion: These findings create awareness of CoCs listed on labels of selected hair relaxers. This justifies the need for consumer education on potentially harmful chemicals and their associated risks. Further, our findings justify the need for laboratory study to evaluate and quantify CoCs that are listed as well as those that are not listed on the label.

Indexed as

Hair PreparationsProduct LabelingAdolescentAdultCross-Sectional StudiesFemaleHair DyesHumansHydrogen-Ion ConcentrationKenyaMiddle AgedSurveys and QuestionnairesYoung AdultHair DyesHair Preparationschemicals of concerncosmeticsHair productshair relaxersingredients labelspersonal care productspH

Identifiers

PMID40308917
PMCPMC12042934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.