ArticleFrontiers in veterinary science2025
Effect of resveratrol supplementation on lipid metabolism in healthy and obese cats.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Plant extracts and phytochemicals in canine and feline mammary cancer models: current evidence and comparative perspectives.Veterinary research communications · 2026Review
- From pathogenesis to prevention: an update on the management of obesity and its associated comorbidities in cats.Frontiers in veterinary science · 2026Review
- Establishing diagnostic criteria for feline obesity using a highly sensitive serum amyloid A assay.Frontiers in veterinary science · 2025Article
- Transcriptomic and metabolomic insights into the synergistic effects of resveratrol and β-hydroxy-β-methylbutyric acid on hepatic function under varying protein diets in Tibetan sheep.Frontiers in nutrition · 2025Article
- Age-related obesity and inflammaging in cats.Frontiers in veterinary science · 2025Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The prevalence of lipid metabolism disorders, including obesity, increases with age in cats and humans. Obesity is a condition characterized by systemic low-grade inflammation and oxidative stress caused by excessive visceral fat accumulation. Resveratrol (RSV), a natural plant polyphenol, modulates the expression of anti-inflammatory factors. This study aimed to investigate the effects of resveratrol supplementation on lipid metabolism in both healthy and obese cats and assess its potential as a dietary supplement for improving lipid metabolism disorders in this population. Methods: Plasma metabolite and hormone concentrations, and enzyme activities were measured in healthy, obese, and overweight cats supplemented with RSV for 4 weeks. RVS was supplemented at 1 mg/kg body weight/day (low dose) and 5 mg/kg/day (high dose) in capsules for 4 weeks. Results: Body weight, body condition score, BUN, and insulin concentrations did not change in obese or overweight cats with RSV supplementation for 4 weeks. Plasma triglyceride, free fatty acids, and serum amyloid A (SAA) concentrations and lactate dehydrogenase (LDH) activities decreased, and adiponectin concentrations increased markedly in obese and overweight cats after RSV supplementation. Discussion: Decreased plasma SAA concentrations and LDH activities and increased plasma adiponectin concentrations in obese and overweight cats seem to be induced by the improvement in liver function and the anti-inflammatory effect of RSV. Moreover, RSV supplementation may be useful in treating lipid metabolism disorders, including obesity, in cats.
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