ArticleInternational journal of nanomedicine2025
Therapeutic Potential of AgNP-Infused Patches in Periodontal Disease: An Observational Study in Albino Rats.
Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Trastuzumab-Conjugated Nanoliposomes for Targeted Capecitabine Delivery to Suppress HER2-Positive Breast Tumor: Efficacy Analysis in NOD SCID Mice Xenografts.International journal of nanomedicine · 2026Article
- The association between periodontal disease and pancreatic cancer: epidemiology, mechanisms, and implications for clinical management.Frontiers in cellular and infection microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Silver nanoparticles (AgNPs) have emerged as a promising therapeutic modality in periodontal disease management due to their potent antimicrobial activity and ability to promote tissue regeneration. This study aimed to evaluate the efficacy of AgNP-infused patches in ligature-induced periodontitis rat model. Methods: AgNPs were synthesized using a green synthesis method with neem ( Results: Characterization by Atomic Force Microscopy revealed spherical AgNPs with an average size of 85 nm, while Field Emission Scanning Electron Microscopy confirmed uniform morphology and size distribution. Production of microporous AgNP patches with uniform nanoparticle dispersion was also validated by Scanning electron microscopy and Energy Dispersive X-ray Analysis. Observational and histopathological analysis revealed significant improvements in gingival and periodontal tissue restoration, inflammation reduction in the AgNP-treated groups compared to untreated and standard-treated groups. Discussion: Notably, the high-dose AgNP patch (1000 mg/kg) treated group exhibited near-complete tissue restoration. These findings highlight the potential of AgNP patch as a localized treatment alternative for periodontal disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.