Evidence map›Paper›PMID 40308631›Full record

ReviewInfection and drug resistance2025

Association Between

Jéssica María Sarmiento-Ordóñez, Dayvid Rafael Brito-Samaniego, Ana Cristina Vásquez-Palacios, Edisson-Mauricio Pacheco-Quito

Abstract readReview
In one paragraph

Review in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Association Between Periodontitis and Mild Cognitive Impairment, Alzheimer's Disease, and Dementia: An Umbrella Review With Evidence Stratification.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Pooled it
  2. Pg-Induced ATR Activation Promotes ESCC Progression via M2 TAM Polarization.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026
    Article
  3. Article
  4. [Oral Aging: Age-Related Changes and Their Association With Systemic Aging].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  5. Review
  6. Article
  7. Is Alzheimer's an Autoimmune Disease?Molecular neurobiology · 2026
    Review
  8. Review
  9. Association between Alzheimer's disease andWorld journal of biological chemistry · 2025
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jéssica María Sarmiento-OrdóñezUnidad Académica de Salud y Bienestar, Facultad de Odontología, Universidad Católica de Cuenca, Cuenca, Ecuador.ORCID 0000-0003-4159-9286
Dayvid Rafael Brito-SamaniegoMinistry of Public Health of Ecuador, Dentistry Department, Cuenca, Ecuador.ORCID 0009-0009-5427-8167
Ana Cristina Vásquez-PalaciosUnidad Académica de Salud y Bienestar, Facultad de Odontología, Universidad Católica de Cuenca, Cuenca, Ecuador.ORCID 0000-0002-8559-2855
Edisson-Mauricio Pacheco-QuitoUnidad Académica de Salud y Bienestar, Facultad de Odontología, Universidad Católica de Cuenca, Cuenca, Ecuador.ORCID 0000-0002-6168-3218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontitis has long been linked to various inflammatory, chronic, and immunological diseases, such as heart disease or diabetes. Recently, there has been increasing scientific interest in the bidirectional relationship that may exist between periodontitis and the presence and progression of Alzheimer's disease (AD), where it is hypothesized that the infiltration of oral microorganisms (mainly Purpose: The purpose of this review is to determine the association between Patients and Methods: It was carried out using different databases such as PubMed, Web of Science, among others, of no more than 10 years old focused on older adult patients who have presented periodontitis and Alzheimer's disease. MESH-indexed terms were used, getting 307 articles. After removing 206 duplicates and applying inclusion criteria (language, relevance, and contribution to the study's objectives), 24 articles were selected for analysis. Conclusion: Evidence has been found that gingipains produced by

Indexed as

Alzheimer’s diseaseolder adultsperiodontitisPorphyromonas gingivalis

Identifiers

PMID40308631
PMCPMC12043021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.