Evidence map›Paper›PMID 40308615›Full record

ReviewFrontiers in immunology2025

Correlation of organelle interactions in the development of non-alcoholic fatty liver disease.

Jiabao Liao, Mengqiu Shao, Ze Zhou, Si Wang, You Lv, Yanming Lu, Fang Yao, Wenting Li, Ling Yang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiabao Liao *First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Mengqiu Shao *First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Ze Zhou *First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Si WangFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
You LvFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Yanming LuFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Fang YaoDepartment of Endocrinology, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, China.
Wenting LiFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Ling YangFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organelles, despite having distinct functions, interact with each other. Interactions between organelles typically occur at membrane contact sites (MCSs) to maintain cellular homeostasis, allowing the exchange of metabolites and other pieces of information required for normal cellular physiology. Imbalances in organelle interactions may lead to various pathological processes. Increasing evidence suggests that abnormalorganelle interactions contribute to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the key role of organelle interactions in NAFLD has not been fully evaluated and researched. In this review, we summarize the role of organelle interactions in NAFLD and emphasize their correlation with cellular calcium homeostasis, lipid transport, and mitochondrial dynamics.

Indexed as

Non-alcoholic Fatty Liver DiseaseOrganellesAnimalsCalciumHomeostasisHumansLipid MetabolismMitochondriaMitochondrial DynamicsCalciumERinteractionsMCSsNAFLDorganelles

Identifiers

PMID40308615
PMCPMC12040704

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.