Evidence map›Paper›PMID 40308484›Full record

ArticleClinical case reports2025

Fulminant Hepatic Failure Following Intentional Iron Overdose-A Case Report.

Hrithik Dakssesh Putta Nagarajan, Ram Vivek Ramamoorthy, Naveen Vishwanath, Miruthula Murugan, Balakrishnan Kamaraj, Shiva Jeyaprakash Narayan Balamurugan, Shubham Kumar, Shilpa Gaidhane, Sanjit Sah, Prakasini Satapathy and 2 more

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hrithik Dakssesh Putta NagarajanMadurai Medical College Madurai Tamil Nadu India.ORCID https://orcid.org/0000-0002-6497-7043
Ram Vivek RamamoorthyMadurai Medical College Madurai Tamil Nadu India.ORCID https://orcid.org/0009-0000-0752-0592
Naveen VishwanathMadha Medical College and Research Institute Chennai Tamil Nadu India.
Miruthula MuruganMadha Medical College and Research Institute Chennai Tamil Nadu India.
Balakrishnan KamarajMadurai Medical College Madurai Tamil Nadu India.
Shiva Jeyaprakash Narayan BalamuruganMadurai Medical College Madurai Tamil Nadu India.
Shubham KumarCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences Saveetha University Chennai India.
Shilpa GaidhaneOne Health Centre (COHERD), Jawaharlal Nehru Medical College Datta Meghe Institute of Higher Education Wardha India.
Sanjit SahDepartment of Paediatrics, Dr. D. Y. Patil Medical College Hospital and Research Centre Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University) Pune Maharashtra India.
Prakasini SatapathyUniversity Center for Research and Development Chandigarh University Mohali Punjab India.ORCID https://orcid.org/0000-0001-7614-8587
Rachana MehtaClinical Microbiology, RDC Manav Rachna International Institute of Research and Studies Faridabad Haryana India.
Amogh VermaSR Sanjeevani Hospital Kalyanpur Siraha Nepal.ORCID https://orcid.org/0000-0003-2499-4874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intentional iron overdose in adults is a rare but formidable clinical challenge, often complicated by delayed presentation and a concealed history of ingestion. We report the case of a 21-year-old male who presented 4 days after consuming large quantities of ferrous sulfate tablets. The initial nonspecific gastrointestinal symptoms progressed to severe jaundice, encephalopathy, and coagulopathy, and the diagnosis was confounded by the patient's denial of suicidal ingestion. By the time iron toxicity was identified, the therapeutic window for early decontamination or parenteral chelation had been passed. Supportive care, including advanced extracorporeal therapies, facilitated hepatic and renal recovery. This case highlights the importance of high clinical suspicion, thorough history taking, and the potential role of salvage therapies in severe late-presenting iron poisoning.

Indexed as

ferrous sulfate poisoningfulminant hepatic failurehemodialysisiron toxicity managementplasma exchange

Identifiers

PMID40308484
PMCPMC12041657

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.