ArticleFrontiers in neurology2025
Post-stroke mortality in ICU patients with serum glucose-potassium ratio: an analysis of MIMIC-IV database.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Article
- Glucose/potassium ratio and a novel combined model for the differential diagnosis of testicular torsion: a retrospective study.Basic and clinical andrology · 2026Article
- Association between blood urea nitrogen-to-potassium ratio trajectories and MAKE-30 risk in critically patients with non-traumatic subarachnoid hemorrhage.Scientific reports · 2026Article
- Serum glucose-to-potassium ratio is associated with delirium and all-cause mortality in intensive care unit patients: insights from the MIMIC database analysis.American journal of translational research · 2026Article
- U shaped relationship between serum glucose potassium ratio and mortality in critically ill patients with toxic encephalopathy.Scientific reports · 2025Article
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Authors and funding
4 authors.
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Abstract
Introduction: Acute ischemic stroke (AIS) patients admitted to the intensive care unit (ICU) have a high mortality rate, necessitating the early identification of those at risk of a poor prognosis. This study investigated the association between the blood glucose-to-potassium ratio (GPR) and the prognosis of AIS patients. Methods: We conducted a retrospective cohort study using data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. The primary outcomes were 28-day, 90-day, and 1-year mortality rates following ICU admission. Multivariate Cox proportional hazards regression models were used to estimate adjusted hazard ratios (HRs) with 95% confidence intervals (CIs). Subgroup analyses, Kaplan-Meier survival curves, and restricted cubic spline models were employed to further evaluate the relationship between the GPR and mortality in AIS patients. Results: A total of 2,636 AIS patients were included in the study, with a mean age of 69.4 ± 15.6 years. The 1-year mortality rate was 36.8% ( Conclusion: The GPR is an independent predictor of poor prognosis in AIS patients admitted to the ICU. Higher GPRs are associated with increased 28-day and 90-day mortality rates, highlighting the potential utility of this ratio in risk stratification and clinical decision-making. A non-linear relationship was observed between the GPR and 365-day mortality, with an inflection point identified at GPR = 2.75.
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