ArticleNeuropsychopharmacology reports2025
Clinical Significance of Psychiatric Comorbidities Among Outpatients With Gambling Disorder in Japan: A 12-Month Follow-Up Study.
Article in Neuropsychopharmacology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association Between Early Dropout from a Gambling Disorder Group Program and Subsequent Loss of Outpatient Contact: A Retrospective Cohort Study.Journal of gambling studies · 2026Article
- Clinical Outcomes and Predictors of Improvement With Virtual Behavioral Health Care for Gambling Disorder: Retrospective Cohort Study.JMIR mental health · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundGambling disorder (GD) is often comorbid with other psychiatric disorders. Previous studies have reported that psychiatric comorbidity increases both treatment dropout and relapse among patients with GD. However, little is known about the effects of comorbidity among outpatients with GD either during or after treatment. This study examined this issue in a clinical setting.
method60 outpatients with GD (men/women, 58/2; average age, 37.9 years) participated in assessments of the course of multidimensional treatment outcomes (i.e., gambling-related variables, social impairment, and depressive symptoms) at three time points (baseline, 3 months, and 12 months). We examined treatment outcomes in GD patients with and without comorbidity.
resultsA total of 58.3% of the patients had comorbidities (major depressive disorder, 26.7%; behavioral addiction, 21.7%; anxiety disorder, 15.0%, etc.), while the dropout rates across the study period were 13.3% at 3 months and 35.0% at 12 months. Statistical analyses indicated that the South Oaks Gambling Screen score and the Sheehan Disability Scale score were significantly reduced at follow-up compared to baseline in both comorbid and non-comorbid outpatients. There was a significant difference for being still in treatment, where the proportion of individuals with comorbid disorders was significantly higher than those without comorbidities at the 12-month compared to the 3-month follow-up. The proportion of all outpatients who remained abstinent from gambling at 12 months was significantly lower compared to baseline and at 3 months.
conclusionsBeing still in treatment for comorbid psychiatric problems may affect the course and outcome of GD treatment.
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