Evidence map›Paper›PMID 40307945›Full record

ArticleAntimicrobial resistance and infection control2025

Management and microbial monitoring of final rinse water for flexible endoscopes in 290 hospitals in Jiangsu Province, China: a multicenter cross-sectional study.

Zhanjie Li, Bo Liu, Qingtang Zhu, Zijun Ge, Feng Zang, Wensen Chen, Yongxiang Zhang, Xiafen Ding, Jing Ding, Weihong Zhang

Abstract readMulticenter Study
In one paragraph

Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhanjie Li *Department of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China. lzj070591@163.com.
Bo Liu *Department of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China.
Qingtang ZhuDepartment of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China.
Zijun GeDepartment of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China.
Feng ZangDepartment of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China.
Wensen ChenDepartment of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China.
Yongxiang ZhangDepartment of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China.
Xiafen DingDepartment of Endoscopy Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China.
Jing DingDepartment of Endoscopy Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China. dragonjing@163.com.
Weihong ZhangDepartment of Infection Control, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China. zhangweihong@jsph.org.cn.

Funding

Chinese Preventive Medicine Association Hospital Infection Department Development Youth Talent Promotion Project CPMA-HAIsC-2024012900108the Jiangsu Province Hospital Management Innovation Research Project JSYGY-3-2023-559the Jiangsu Provincial Association for Science and Technology Young Science and Technology Talent Support Project (Health Field) JSTJ-2023-WJ006the Jiangsu Science and Technology Think Tank Program (Youth) Project JSKX24055the Project of Chinese Hospital Reform and Development Institute, Nanjing University NDYG2023039the Third Outstanding Young and Middle-aged Talents Training Program of Jiangsu Provincial People's Hospital YNRCQN0314the Young Scholars Fostering Fund of the First Affiliated Hospital of Nanjing Medical University PY2022017
6 · The paper itself

Abstract

backgroundThere is a lack of a universally accepted standard or guideline for the frequency of disinfection in purified water pipelines. Furthermore, there is no standardized method for detecting microorganisms in the final rinse water utilized for endoscope cleaning.This study aims to examine the current management and microbial monitoring practices concerning the final rinse water used for flexible endoscope cleaning in medical institutions.

methodsA questionnaire was designed using a convenience sampling method to gather data on the maintenance and microbial monitoring of final rinse water for flexible endoscopes in 290 medical institutions across Jiangsu Province, China.

resultsPurified water is used for endoscope rinsing by 93.45% of institutions, with 78.62% employing centralized water supply. Membrane filtration devices at the terminal are installed by 82.07%, mainly with a 0.2μm pore size (76.47%), and are replaced quarterly (32.77%). Disinfection devices are present at 52.76% of terminals, with varied disinfection frequencies; chlorine-containing disinfectants (48.15%) and peracetic acid (34.92%) are predominant. Inadequate disinfection, filter membrane neglect, sampling contamination, and biofilm formation are identified as reasons for non-compliant final rinse water. Actions include filter replacement, pipeline disinfection, and flushing. Microbial mornitoring occurs quarterly (70.96%), with faucet outlets as primary sampling sites. Standards are based on 10cfu/100ml (87.58%), using membrane filtration (40.81%) and nutrient agar plates (82.72%). A cultivation period of 2 days predominated (72.43%), with a temperature range of 35-37°C (76.47%).

conclusionWhile purified water and terminal filters are common for final rinsing of endoscopes, there is variation in maintenance and supply line disinfection. Current microbiological methods' reliability is considered low, necessitating further research to establish unified standards for effective endoscope final rinse water management and monitoring.

Indexed as

DisinfectionEndoscopesWater MicrobiologyBiofilmsChinaCross-Sectional StudiesDisinfectantsEquipment ContaminationFiltrationHospitalsHumansSurveys and QuestionnairesDisinfectantsFinal rinse waterFlexible endoscopyManagementMicrobial monitoring

Identifiers

PMID40307945
PMCPMC12044760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.