ArticleVirology journal2025
Fulminant hepatitis and multi-organ failure following varicella zoster virus infection in an adult with G6PD deficiency: a case report.
Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundVaricella zoster virus (VZV) infection in adults can lead to severe complications, particularly in those with underlying comorbidities. This case report presents a rare instance of VZV-associated fulminant hepatitis progressing to multi-organ failure in a 27-year-old female with glucose-6-phosphate dehydrogenase (G6PD) deficiency. CASE PRESENTATION: The patient presented with a generalized rash and rapidly developed acute liver failure, coagulopathy, and renal dysfunction. Despite aggressive management, including intravenous immunoglobulin therapy and supportive care, the patient's condition deteriorated, ultimately resulting in mortality.
conclusionsThis case highlights the potential for severe hepatic complications in adult VZV infections, especially in patients with G6PD deficiency, and underscores the importance of early recognition and aggressive management. It also raises awareness about the risks associated with concomitant medication use, including over-the-counter drugs and herbal supplements, in the context of acute viral infections. CLINICAL TRIAL NUMBER: Not applicable.
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