Evidence map›Paper›PMID 40307840›Full record

ArticleBMC sports science, medicine & rehabilitation2025

Physical fitness predicts post-esophagectomy complications after chemoradiotherapy: a pilot study.

Chien-Hung Chiu, Wei-Yang Chang, Lan-Yan Yang, Yin-Kai Chao, Wei-Hsun Chen, Yun-Hen Liu, Ya-Tzu Tsao, Yu-Ling Chang, Shu-Chun Huang

Abstract read
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chien-Hung ChiuDivision of Thoracic Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Wei-Yang ChangClinical Trial Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Lan-Yan YangDivision of Clinical Trial, Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Yin-Kai ChaoDivision of Thoracic Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Wei-Hsun ChenDivision of Thoracic Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Yun-Hen LiuDivision of Thoracic Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Ya-Tzu TsaoDepartment of Medical Nutrition Therapy, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Yu-Ling ChangChang Gung University, Taoyuan, Taiwan.
Shu-Chun HuangDepartment of Physical Medicine and Rehabilitation, New Taipei Municipal Tucheng Hospital, Chang Gung Memorial Hospital, New Taipei City, 333423, Taiwan. h0711@ms13.hinet.net.

Funding

Chang Gung Memorial Hospital, Linkou CMRPVVK0111-3Chang Gung Memorial Hospital, Linkou CORPG3J0621Ministry of Health and Welfare MOHW113-TDU-B-212-114010Ministry of Science and Technology MOST 108-2314-B-182A-061National Science and Technology Council MOST 109-2314-B-182A-074-MY3
6 · The paper itself

Abstract

backgroundEsophagectomy following neoadjuvant chemoradiotherapy or definitive chemoradiotherapy has been shown to yield favorable oncological outcomes in patients with locally advanced esophageal squamous cell carcinoma. However, postoperative complications are frequent and can adversely affect patient survival. This study aimed to identify physical fitness factors across multiple domains associated with major postoperative complications.

methodsThis study enrolled patients with esophageal squamous cell carcinoma who were treated with neoadjuvant chemoradiotherapy or definitive chemoradiotherapy and underwent esophagectomy between 2020 and 2022. Multivariate logistic regression analysis was conducted to identify the factors associated with major postoperative complications. Additionally, a tree-based learning process was employed to assess all the variables influencing major complications.

resultsA total of 142 esophageal cancer patients who underwent esophagectomy were screened. Of these, 72 eligible patients were included in the study, and 29 (40.2%) experienced major postoperative complications. In the full model, factors such as low body weight, low body mass index, low peak oxygen consumption (V̇O

conclusionsPatients with low AV̇P, high EqO

Indexed as

ChemoradiotherapyComplicationsEsophageal cancerEsophagectomyPhysical fitness

Identifiers

PMID40307840
PMCPMC12042600

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.