Evidence map›Paper›PMID 40307785›Full record

ArticleBMC veterinary research2025

Detection of canine distemper virus (CDV) neutralising antibodies in small ruminants during peste-des-petits-ruminants virus (PPRV) surveillance in Zambia.

Sara Lysholm, Nicola Logan, Johanna F Lindahl, Mikael Berg, Elin Johansson, Pernilla Karlsson Bergkvist, George Dautu, Ricky Chazya, Brian J Willett, Musso Munyeme and 1 more

Abstract read
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In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara LysholmDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, 75007, Uppsala, Sweden.
Nicola LoganCentre for Virus Research, MRC-University of Glasgow, University of Glasgow, Glasgow, G611QH, UK.
Johanna F LindahlAnimal and Human Health Program, Department of Biosciences, International Livestock Research Institute, Nairobi, 00100, Kenya.
Mikael BergDepartment of Animal Health and Antimicrobial Strategies, Swedish Veterinary Agency, Uppsala, 75189, Sweden.
Elin JohanssonDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, 75007, Uppsala, Sweden.
Pernilla Karlsson BergkvistDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, 75007, Uppsala, Sweden.
George DautuDepartment of Veterinary Services, Ministry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka, 50060, Zambia.
Ricky ChazyaDepartment of Veterinary Services, National Livestock Epidemiology and Information Centre, Lusaka, 50060, Zambia.
Brian J WillettCentre for Virus Research, MRC-University of Glasgow, University of Glasgow, Glasgow, G611QH, UK.
Musso MunyemeDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, 32379, Zambia.
Jonas Johansson WensmanDepartment of Animal Biosciences, Swedish University of Agricultural Sciences, Uppsala, 75007, Sweden. jonas.wensman@slu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine distemper virus (CDV) is endemic in Zambia, while peste-des-petits-ruminants virus (PPRV) has not been detected. This study screened 962 farmed goats and 237 small ruminants at informal markets for PPRV antibodies using c-ELISA. A subset (n = 29) was re-analysed with virus neutralisation assays (VNA) for antibodies to PPRV and CDV due to cross-reactivity concerns. c-ELISA indicated 6.44% PPRV seroprevalence on farms and 3.80% at markets. While VNA detected no PPRV antibodies, 45% (13/29) tested positive for CDV, possibly suggesting cross-reactivity. Given the study's limitations, further research is needed to determine whether PPRV is present in Zambia and assess potential cross-reactivity.

Indexed as

Antibodies, NeutralizingAntibodies, ViralDistemperDistemper Virus, CanineGoat DiseasesPeste-des-Petits-RuminantsPeste-des-petits-ruminants virusSheep DiseasesAnimalsEnzyme-Linked Immunosorbent AssayGoatsSeroepidemiologic StudiesSheepZambiaAntibodies, NeutralizingAntibodies, ViralCanine distemperCanine distemper virusGoatsLivestock marketsMorbillivirusPeste-des-petits-ruminantsPeste-des-petits-ruminants virusSheepSmall ruminantsZambia

Identifiers

PMID40307785
PMCPMC12042581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.