Evidence map›Paper›PMID 40307760›Full record

ArticleBMC ophthalmology2025

A retrospective study of posterior vitreous detachment in patients with non-arteritic anterior ischemic optic neuropathy referred to Rasoul Akram hospital in 2022-2023.

Mina Rabbani, Mostafa Soltan Sanjari, Ali Sadeghi, Hanieh Neshastesaz, Zahra Rabbani, Salar Khiabani

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Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Authors and funding

6 authors.

Mina RabbaniSchool of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mostafa Soltan SanjariEye Research Center, Eye Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ali SadeghiEye Research Center, The Five Senses Health Institute, School of Medicine, Moheb Kowsar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Hanieh NeshastesazSchool of Medicine, Iran University of Medical Sciences, Tehran, Iran. neshastesaz.hanieh@gmail.com.
Zahra RabbaniDepartment of Pharmacy, School of Pharmacy, Islamic Azad University of Pharmacy, Tehran, Iran. Rabbani_zahra77@yahoo.com.
Salar KhiabaniSchool of Medicine, Iran University of Medical Sciences, Tehran, Iran. salarkhiabani76@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrevious studies have provided evidence that non-arterial ischemic optic neuropathy (NAION), vitreous traction, and posterior vitreous detachment (PVD) may be related; However, a detailed description of the predictive features of PVD in these patients has been provided in a few studies so far. By conducting this study, we decided to take a positive step in clarifying the pathophysiology of the relationship between the two disorders and increasing the patient's quality of life through early detection.

methodsIn this descriptive cross-sectional study, after obtaining the necessary permits from the Ethics Committee of Iran University of Medical Sciences, the information in the clinical records of patients with ischemic optic neuropathy referred to Rasoul Akram Hospital from March 2022 to December 2023 was analyzed. Exclusion criteria included having diabetes, intraocular bleeding, intraocular inflammation, and a history of eye trauma or surgery. Moreover, patient information including age, gender, presence of papillary edema, optic atrophy, intracranial pressure (ICP) rise, and presence of PVD was extracted from the file. At the end, the data collected from the patients was entered into the statistical software SPSS version 26 and employed Chi-square tests for analysis.

resultsPVD was seen in 18 patients (18.9%) out of 95 patients evaluated. A statistically significant relationship was seen only between the age group of patients with the presence of PVD (P = 0.028); In this way, with increasing age, the percentage of PVD from 0.0% in the age group below 18 years, to 7.1% in the age group 18-38 years, to 26.2% in the age group 38-58 years and to 7. 35% was significantly increased in the age group of 58 years respectively. Meanwhile, no statistically significant relationship was found between other variables including gender, the presence of papillary edema, optic atrophy, and ICP rise with the presence of PVD (P > 0.05).

conclusionIn patients with optic nerve ischemic neuropathy, the incidence of PVD increases significantly with age. Therefore, to find a causal relationship between PVD and optic nerve ischemic neuropathy, an age-related factor should be sought. Hence, future research should be designed and implemented to compare the mechanism of PVD and non-arteritic ischemic optic neuropathy (NAION) at the same time in different age groups.

Indexed as

Optic Neuropathy, IschemicVitreous DetachmentAdolescentAdultAgedCross-Sectional StudiesFemaleHumansIranMaleMiddle AgedRetrospective StudiesYoung AdultOphthalmologyOptic nerve ischemic neuropathyPosterior vitreous detachment

Identifiers

PMID40307760
PMCPMC12044946

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