ArticleBMC infectious diseases2025
Evaluation of the performance of disease severity indices (SOFA, SAPS III, and MPM II) for the prediction of mortality rate in COVID-19 patients admitted to the intensive care units: a retrospective cross-sectional study.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Prognostic Value of Serial Lactate Dehydrogenase Measurements for Determining Early Mortality in ICU Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Regional citrate versus systemic heparin anticoagulation in continuous renal replacement therapy for sepsis-associated acute kidney injury: A retrospective cohort study of short-term outcomes.The Journal of international medical research · 2026Article
- Severity Scores in SARS-CoV-2 Infection-A Comprehensive Bibliometric Review and Visualization Analysis.Epidemiologia (Basel, Switzerland) · 2026Review
- A nomogram for predicting ARDS progression and need for invasive ventilation in COVID-19 patients using plasma hyaluronic acid and clinical scores.Frontiers in cellular and infection microbiology · 2026Article
- Early Diagnostic Markers and Risk Stratification in Sepsis: Prognostic Value of Neutrophil-to-Lymphocyte Ratio, Platelets, and the Carmeli Score.Biomedicines · 2025Article
- Prediction of Hyperinflammatory Phenotypes in Critically Ill Patients via Routine Clinical Data and IL-6: Towards Personalized Anti-Inflammatory Therapy.International journal of molecular sciences · 2025Article
- Predictive value of seven scoring systems for 28-day mortality in ICU patients with Sleep apnea-hypopnea syndrome (SAHS) and clinical indicators.European journal of medical research · 2025Article
- Evaluation of MODS and survival outcome in infectious diseases using SOFA and SAPS scores.Bioinformation · 2025Article
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4 authors.
Funding
Abstract
backgroundThe COVID-19 pandemic created a high demand for hospital beds and intensive care, which led to the collapse of healthcare systems. Therefore, it is critical to identify factors associated with increased mortality in patients to prioritize high-risk individuals.
aimGiven the potential for similar pandemics in the future, this study investigated predictors of mortality in ICU patients with COVID-19 and their correlation with mortality rates. STUDY
designIn this retrospective study, all patients admitted to the ICUs of Ghaem and Imam Reza tertiary hospitals in Mashhad with a definitive diagnosis of COVID-19 from March 21, 2020, to December 1, 2021, were evaluated for disease severity assessment criteria, including SOFA, SAPS III, and MPM II.
resultsOne hundred seventy-two patients with COVID-19 who were admitted to the ICU were evaluated (147 patients in the non-survivor group and 25 patients in the survivor group. The median SAPS, SOFA, and MPM scores were significantly higher in non-survivors (p<0.001 in all cases). Higher SAPS, SOFA, and MPM were associated with an increased risk of mortality in COVID-19 patients in the ICU. The best cut-off points for the three scoring systems, SAPS, SOFA, and MPM, were 39, 6, and 13.7, respectively. The AUC value of the SOFA score was significantly higher than the SAPS (P = 0.0274) and MPM (P = 0.0209) scores.
conclusionCOVID-19 patients admitted to the ICU with higher SOFA, MPM, and SAPS scores suffered from higher mortality rates. Because the SOFA score showed high predictive accuracy, this scoring system should be considered a priority as an essential tool in triaging and managing critically ill COVID-19 patients.
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