ArticleBMC infectious diseases2025
Seroprevalence of HIV, HBV, HCV and Syphilis among blood donors in a Nigerian tertiary medical centre.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Seroprevalence of Hepatitis B and C Viral Infections Among Patients With Diabetes Mellitus in Africa: A Systematic Review and Meta-Analysis.Journal of the International Association of Providers of AIDS CarePooled it
- Prevalence and socio-demographic factors associated with transfusion transmissible infections among voluntary blood donors in Kigali, Rwanda.BMC infectious diseases · 2026Article
- Prevalence of transfusion-transmissible infections and associated sociodemographic risk factors among blood donors at a tertiary care hospital in Lahore, Pakistan.BMC infectious diseases · 2026Article
- Association between ABO/Rh blood groups and transfusion-transmitted infections among Turkish blood donors: a comprehensive demographic analysis (2015-2021).BMC infectious diseases · 2026Article
- Article
- Sero-prevalence and associated factors of transfusion-transmitted infections of HBV, HCV, HIV, and syphilis among voluntary blood donors in Gondar District Blood Bank, Ethiopia: a retrospective study.BMC infectious diseases · 2025Article
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Abstract
backgroundTransfusion-transmitted infections (TTIs), such as HIV, HBV, HCV, and Syphilis, present considerable difficulties in maintaining blood quality despite the critical role of blood transfusion in emergency medical care. This study aims to ascertain the prevalence of these infections and the factors that increase their risk among those who donate blood.
methodsA cross-sectional study was conducted at the Federal Medical Center in Azare, involving 400 blood donors. Serological tests were conducted for HBV, HCV, HIV, and syphilis, and sociodemographic data was collected through a structured questionnaire. The univariate and multivariate logistic regression tests were employed to detect associated risk factors, with a significance level set at P < 0.05.
resultOf the total blood donors, 17.00% (68/400) tested positive for at least one TTIs. The presence of HIV, HBV, HCV, and syphilis was identified in 2.8% (11/400), 8.3% (33/400), 1.8% (7/400), and 4.3% (17/400) of the donors, respectively. Multivariate analysis, after adjustments with various variables, indicates only commercial blood donors [Adjusted Odds Ratio (AOR) (95% CI): 14.63 (1.76-121.27)] and multiple sexual partners [AOR (95% CI): 5.40 (1.28-22.70)] were associated with HIV, while blood transfusion and piercing or tattoo were associated with HBV. Multiple sexual partners and a history of STDs were associated with syphilis infection.
conclusionTTIs such as HIV, HBV, HCV, and syphilis were detected among the blood donors, with HBV being the most common. The findings highlight a gender disparity in blood donation, with voluntary donors comprising the majority; nevertheless, commercial donors had the highest prevalence of TTIs. Enhanced donor screening and public awareness are crucial for blood safety. CLINICAL TRIAL NUMBER: Not applicable.
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