Evidence map›Paper›PMID 40307611›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Clinicopathological characteristics and management of ceruminous adenomas in the external auditory canal: a retrospective analysis of six cases.

Xiaoli Cai, Yan Zhao, Shuang Liu, Fangru Dong, Jie An, Yanli Liu, Lin Liu

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoli CaiDepartment of Pathology, Bethune International Peace Hospital, Shijiazhuang, Hebei, 050000, China.
Yan ZhaoDepartment of Orthopaedics, Bethune International Peace Hospital, No. 398 Zhongshan West Road, Qiaoxi District, Shijiazhuang, Hebei, 050000, China. zhaoyyymed@outlook.com.ORCID http://orcid.org/0009-0008-4854-1638
Shuang LiuDepartment of Pathology, Bethune International Peace Hospital, Shijiazhuang, Hebei, 050000, China.
Fangru DongDepartment of Otolaryngology, Bethune International Peace Hospital, Shijiazhuang, Hebei, 050000, China.
Jie AnDepartment of Pathology, Bethune International Peace Hospital, Shijiazhuang, Hebei, 050000, China.
Yanli LiuDepartment of Pathology, Bethune International Peace Hospital, Shijiazhuang, Hebei, 050000, China.
Lin LiuDepartment of Pathology, Bethune International Peace Hospital, Shijiazhuang, Hebei, 050000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCeruminous adenomas (CA) are rare neoplasms of the external auditory canal (EAC), and their nonspecific symptoms frequently contribute to diagnostic challenges in clinical practice. By examining the clinical features, diagnostic considerations, and therapeutic approaches for these tumors, the findings aim to improve understanding of these tumors and improve clinical outcomes. CASE PRESENTATION: A retrospective analysis was conducted on six individuals diagnosed with CAs of the EAC at a single institution between January 2010 and January 2023. Clinical data, histopathological characteristics, and immunophenotypic findings were reviewed, along with a relevant literature analysis. Of the six cases, three involved simple CAs, one was associated with concurrent adenoid cystic carcinoma, and two exhibited localized areas of high mitotic activity, necessitating vigilant follow-up. No recurrences were observed during the follow-up period. Symptomatically, one patient reported occasional tinnitus, while another presented with ear discharge.

conclusionThe diagnosis of ceruminous gland tumors requires a multidisciplinary approach, incorporating clinical evaluation, imaging studies, and histopathological examination. CAs of the EAC are uncommon, with reports in the literature indicating a risk of recurrence and potential for malignancy. Surgical management should involve wide excision with wound repair, followed by close postoperative monitoring to ensure early detection of any recurrence.

Indexed as

AdenomaEar CanalEar NeoplasmsCarcinoma, Adenoid CysticCerumenHumansRetrospective StudiesCeruminous gland tumorExternal auditory canalImmunohistochemistryNeo-organisms of the external auditory canalSurgical resection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.