Evidence map›Paper›PMID 40307606›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

A systematic review on the role of the endoscope in the surgical management of cerebellopontine angle tumors: is it time to draw the conclusion?

Raffaele De Marco, Sébastien Froelich, Andrea Albera, Diego Garbossa, Francesco Zenga

Abstract readSystematic Review
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raffaele De MarcoDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, Via Cherasco, 15, Turin, 10126, Italy. raffaele.demarco@unito.it.ORCID http://orcid.org/0000-0001-5187-4689
Sébastien FroelichDepartment of Neurosurgery, Lariboisière Hospital, Paris, France.
Andrea AlberaDivision of Otorhinolaryngology, Department of Surgical Sciences, University of Turin, Turin, Italy.
Diego GarbossaDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, Via Cherasco, 15, Turin, 10126, Italy.
Francesco ZengaPituitary and Skull Base Surgery Unit, "Città della Salute e della Scienza" University Hospital, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe use of the endoscope has brought major changes in skull base surgery in the last decades. In the cerebellopontine angle (CPA), it has shown few advantages over microscopic surgery alone, evolving towards a full-endoscopic surgery for neurovascular conflicts and tumors. This review aims to systematically analyze the literature about the use of the endoscope in the cerebellopontine angle tumors.

methodsPubmed/Medline and Embase databases were investigated applying PRISMA guidelines without time restrictions to find all adult patients affected by an extra-axial cerebellopontine angle tumor (vestibular schwannoma, meningioma, epidermoid tumor, or other extra-axial lesions) treated using only the endoscope (full-endoscopic, FE or endoscopic-controlled, EC) or with endoscopic assistance (EA).

resultsAfter article selection, a total of 2489 patients have been treated for a CPA lesion using the endoscope: 2054 vestibular schwannomas (VS), 368 epidermoid tumors (ET), 41 meningiomas and 26 among other pathologies. The retrosigmoid approach was the most frequently employed surgical corridor, irrespective of lesion type, for both full-endoscopic and endoscopic-assisted procedures. Although a great heterogeneity should be highlighted among the selected series of VS (1539), a weighted average of 92.5% of gross total resection (GTR) was obtained and 90% out of 1332 showed a good facial nerve outcome when comparable. Advantages in term of recognition of residuals have been described for the CPA meningiomas and multicompartmental epidermoid tumors with origin from CPA cistern, without increasing the risk of complications.

conclusionsDespite different accepted advantages, the number of tumors in which the endoscope has been included among the surgical armamentarium is still limited compared to the number of the full-microscopic resections. After almost 30 years since its value was recognized, the number of prospective and case-control studies is still scarce to affirm a real benefit leading to its routinary use.

Indexed as

Cerebellar NeoplasmsCerebellopontine AngleEndoscopesEndoscopyNeuroma, AcousticHumansEndoscopeEpidermoid tumorFacial nerveMeningiomaVestibular schwannoma

Identifiers

PMID40307606
PMCPMC12605435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.