Article in Experimental & molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Mohammad El-HarakehKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.ORCID http://orcid.org/0000-0003-3014-3937
Felipe Rodriguez-TiradoKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.ORCID http://orcid.org/0000-0002-6554-8187
Andrew J HardmanKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Alexa MiehlsKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Oumoulkhairy CamaraKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Kelly M GroundsKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Glenis TocajKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.ORCID http://orcid.org/0009-0000-4715-2480
Macie KercsmarKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Birong LiKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Xin WangKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.ORCID http://orcid.org/0000-0003-1456-335X
Brian BecknellKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Ashley R JacksonKidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA. Ashley.Jackson@nationwidechildrens.org.ORCID http://orcid.org/0000-0002-1571-3906
Funding
Novel roles for urothelium during urinary tract obstructionR01DK125469 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BECKNELL, BRIAN · 2020 to 2024
$2.1M
Defining the renal urothelium progenitor and its regulation during development and repairK01DK126991 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI JACKSON, ASHLEY R. · 2021 to 2025
$728k
The University of Pittsburgh Summer Research Internship Program kidney workshop (SRIP-Kid)R25DK119180 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACQUELINE HO, Sunder Sims-Lucas · 2021 to 2026
$648k
Context Specific Roles of Renal Urothelial Cells in Development and Obstructive NephropathyF32DK115085 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI JACKSON, ASHLEY R. · 2017 to 2019
$179k
NIDDK NIH HHS F32 DK115085NIDDK NIH HHS K01 DK126991NIDDK NIH HHS R01 DK125469NIDDK NIH HHS R25 DK119180U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) F32-DK115085U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) K01-DK126991U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R01-DK125469U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R25-DK119180
6 · The paper itself
Abstract
Urinary tract obstruction (UTO) is a common cause of kidney injury that can result in chronic kidney disease and end-stage renal disease. Heterogeneity in the extent of obstructive renal damage in humans with UTO implies the existence of unknown mechanisms that protect against or accelerate kidney injury. Prior studies show that congenital and acquired UTO initiate a conserved, protective program of renal urothelium remodeling that culminates in expansion of uroplakin (UPK)
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
PPARγ promotes urothelial remodeling during urinary tract obstruction. · full record | OpenQuestion