Evidence map›Paper›PMID 40307540›Full record

ReviewClinical rheumatology2025

A bibliometric analysis of rheumatology: knowledge structure and research trends of RNA-Binding proteins in rheumatic diseases.

Wei Zhang, Jiaqi Song, Shuyuan Xian, Sujie Xie, Yifan Liu, Yuntao Yao, Xirui Tong, Xinru Wu, Yuanan Li, Haoyu Zhang and 6 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wei Zhang *Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Jiaqi Song *Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Shuyuan Xian *Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Sujie Xie *Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Yifan LiuDepartment of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Yuntao YaoDepartment of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Xirui TongDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Xinru WuShanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Yuanan LiShanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Haoyu ZhangShanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Bingnan LuDepartment of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Jiajie ZhouShanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Yibin ZhouShanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Dayuan XuDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China. dxdy2014@163.com.
Runzhi HuangDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China. runzhihuang2022@163.com.
Shizhao JiDepartment of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China. shizhaoji2022@163.com.ORCID http://orcid.org/0000-0002-5083-288X

Funding

National Natural Science Foundation of China 81971836Program of Shanghai Academic Research Leader 23XD1425000Shanghai Rising-Star Program (Sailing Special Program) No. 23YF1458400
6 · The paper itself

Abstract

backgroundRheumatic disease is a kind of disease dominated by inflammatory lesions of connective tissue and abnormal immune function. It mostly belongs to autoimmune diseases or connective tissue diseases affecting multiple organs. Meanwhile, understanding the role of RNA-binding proteins (RBPs) in pathogenesis is rapidly developing. This study aims at summarizing the hotspots in rheumatology studies related to RBPs.

methodsScientific papers on RBPs related to rheumatology between 1982 and 2022 were gathered from the Web of Science database. The data analysis and visualization were obtained using the Bibliometrix package. Bibliometrix package was used to analyze bibliometric indicators and visualize the trends and hotspots of the research.

resultsA total of 964 articles met the requirement. From 1982 to 2022, the USA and Anhui Medical University were the most productive country and institution, respectively, in this field. Arthritis and Rheumatism, Annals of the Rheumatic Diseases and Arthritis & Rheumatology were the top three periodicals obtained by Bradford's law. Co-word analysis divided the keywords into three clusters, focusing on diagnosis and classification of Systemic Lupus Erythematosus, pathogenesis of osteoarthritis and pathogenesis of Rheumatoid Arthritis, respectively. Trend topic analysis revealed that pathogenesis and classification of rheumatic diseases might be the research trend.

conclusionFocusing on RBPs in rheumatic diseases, we illustrated the evolution of this field and predicted future research hotspots. The research trend topics have evolved towards clinical classification and pathogenesis at the molecular and genetic level. The pathogenic mechanism in rheumatic diseases will continue to be a hotspot in the future. Besides, the classification of Systemic Lupus Erythematosus patients may be another hotspot. Researchers are recommended to pay more attention to hotspots demonstrated in the future. Key Points • Bibliometrix package was used to analyze bibliometric indicators and visualize the trends and hotspots of the research. • Focusing on RBPs in rheumatic diseases, we illustrated the evolution of this field and predicted future research hotspots. • The research trend topics have evolved towards clinical classification and the pathogenesis at the molecular and genetic level. • The pathogenic mechanism in rheumatic diseases will continue to be a hotspot in the future.

Indexed as

BibliometricsBiomedical ResearchRheumatic DiseasesRheumatologyRNA-Binding ProteinsHumansRNA-Binding ProteinsBibliometricsRheumatic diseasesRheumatologyRNA-binding proteins (RBPs)

Identifiers

PMID40307540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.