ArticleScientific reports2025
Global burden of female infertility attributable to sexually transmitted infections and maternal sepsis: 1990-2021 and projections to 2050.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Aetiological pattern of infertility cases managed at the University of Ilorin Teaching Hospital in Ilorin, North-Central Nigeria: a 3-year retrospective study.BMC women's health · 2026Article
- Association between abdominal surgical incision type and midline intraperitoneal adhesion occurrence, findings from laparoscopic evaluation in a low-resource setting; a retrospective cohort of laparoscopic evaluations.BMC women's health · 2026Article
- The Influence of Sexually Transmitted Bacteria and Human Papillomavirus on Sperm Parameters: Data from a Preliminary Study.Medicina (Kaunas, Lithuania) · 2026Article
- Global, Regional and National Burden of Pelvic Inflammatory Disease: Trend Projections and Health Inequality Analysis, 1990-2021.International journal of women's health · 2026Article
- Prevalence of infertility and its risk factors in Sub-Saharan Africa: a systematic review and meta-analysis.Contraception and reproductive medicine · 2025Article
- Enhancing the precision of male fertility diagnostics through bio inspired optimization techniques.Scientific reports · 2025Article
- Editorial: Lifestyle and environmental factors and human fertility.Frontiers in endocrinology · 2025Article
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Authors and funding
3 authors.
Funding
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Abstract
Infectious diseases, such as sexually transmitted infections (STIs) and maternal sepsis, are major contributors to female infertility, creating a substantial burden on women of reproductive age. Based on Global Burden of Disease (GBD) 2021, this study analyzed the global trends and regional disparities in infection-related infertility for women aged 15-49 and projected future burdens. Our result showed that from 1990 to 2021, global age-standardized prevalence rate (ASPR) rose from 839.52 to 982.37 per 100,000 with estimated annual percentage change (EAPC) (0.26 [0.19 to 0.33]), and years lived with disability (YLDs) increasing from 62.81 to 106.69 thousand (EAPC 0.23 [0.16 to 0.31]), and was predicted to continue rising from 2022 to 2050. The disease burden showed significant regional disparities, low socio-demographic index (SDI) regions had the highest ASPR (1247.25 per 100,000 [1085.17 to 1443.57]) but also the fastest decline (EAPC -1.17 [-1.34 to -0.99]), and Western Sub-Saharan Africa (ASPR 1,925.52 [1655.35 to 2241.71] per 100,000) are the regions with highest burden. The disease burden increased with age, peaking at 40-44 years, and was inversely associated with SDI. These findings provide essential insights for policymakers to develop targeted strategies to prevent and control infection-related infertility, particularly in low-SDI regions.
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