Evidence map›Paper›PMID 40307038›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Varicella Development after Infliximab Therapy for Refractory Pouchitis in Post-surgical Ulcerative Colitis.

Kae Ishii, Shuko Iwatani, Takuro Kawaguchi, Noriaki Ito, Keita Sekiya, Aya Tanaka, Tatsuro Nagaoka, Hiroki Nakamura, Toshihiro Imai, Shuji Wakamatsu and 5 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kae IshiiDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Shuko IwataniDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Takuro KawaguchiDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Noriaki ItoDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Keita SekiyaDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Aya TanakaDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Tatsuro NagaokaDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Hiroki NakamuraDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Toshihiro ImaiDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Shuji WakamatsuDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Akihiko SakataniDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Akira MaekawaDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Kiyoshi IwahashiDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Masanori MiyazakiDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.
Hideki IijimaDepartment of Gastroenterology, Osaka International Medical and Science Center, Osaka Keisatsu Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A boy in his late teens had undergone proctocolectomy for refractory ulcerative colitis eight months ago. Two months earlier, he had developed pouchitis and received intensive treatment with infliximab (IFX). Two days after the IFX injection, a fever and generalized rash appeared. Varicella zoster virus (VZV) antigen positivity in the blisters led to a diagnosis of varicella. Based on the history of VZV vaccination, environmental conditions, and VZV antibody titers in the early stages of the disease, VZV reactivation was suggested. The possibility of varicella should be considered when blisters occur in immunosuppressed patients, although this is rare.

Indexed as

ChickenpoxColitis, UlcerativeGastrointestinal AgentsInfliximabPouchitisAdolescentHerpesvirus 3, HumanHumansMaleGastrointestinal AgentsInfliximabimmunosuppressive therapyinfliximabpouchitisreactivationulcerative colitisvaricella

Identifiers

PMID40307038
PMCPMC12120208

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.