Evidence map›Paper›PMID 40306978›Full record

ArticleGut2025

British Society of Gastroenterology guidelines on colorectal surveillance in inflammatory bowel disease.

James Edward East, Morris Gordon, Gaurav Bhaskar Nigam, Vassiliki Sinopoulou, Adrian C Bateman, Shahida Din, Marietta Iacucci, Misha Kabir, Christopher Andrew Lamb, Ana Wilson and 18 more

Registry-linked trialAbstract read
In one paragraph

Article in Gut, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07694362 (Narrow Band Imaging Versus Artificial Intelligence for Colonic Surveillance in Inflammatory Bowel Disease), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07694362 nacompletednot on this map

Narrow Band Imaging Versus Artificial Intelligence for Colonic Surveillance in Inflammatory Bowel Disease: a Prospective, Randomized, Crossover Study The CLEAR-IBD Trial (Colorectal Lesion Evaluation Assisted by Real-time AI in Inflammatory Bowel Disease)

TypeinterventionalSponsorVall d'Hebron Institute ResearchRan2025 to 2026Enrolled60ConditionsInflammatory Bowel Disease (Crohn&#39, s Disease and Ulcerative Colitis), Ulcerative Colitis (UC), Crohn's Disease ColonArmsENDO-AID CADe System (Olympus, Tokyo, Japan) (AI device)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Predictors of early cancer burden inEClinicalMedicine · 2026
    Article
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Review
  13. Selective Drug-Free Active Surveillance in Ulcerative Colitis: Biomarker-Guided, Patient-Centered Approach.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Review
  14. New Technologies for IBD Endoscopy.Journal of clinical medicine · 2026
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

James Edward EastTranslational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK james.east@ndm.ox.ac.uk.ORCID http://orcid.org/0000-0001-8035-3700
Morris GordonSchool of Medicine, University of Central Lancashire, Preston, UK.ORCID http://orcid.org/0000-0002-1216-5158
Gaurav Bhaskar NigamTranslational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-4699-2263
Vassiliki SinopoulouSchool of Medicine, University of Central Lancashire, Preston, UK.
Adrian C BatemanDepartment of Cellular Pathology, University Hospital Southampton NHS Foundation Trust, Southampton, Southampton, Hampshire, UK.
Shahida DinThe Edinburgh IBD Unit, Western General Hospital, Edinburgh, UK.ORCID http://orcid.org/0000-0003-2855-3400
Marietta IacucciAPC Microbiome Ireland, College of Medicine and Health, University College Cork, Cork, Ireland.ORCID http://orcid.org/0000-0002-3142-9550
Misha KabirDivision of Gastrointestinal Services, University College Hospitals NHS Trust, London, UK.
Christopher Andrew LambTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0002-7271-4956
Ana WilsonDepartment of Gastroenterology, St Mark's Hospital and Academic Institute, London, UK.
Ibrahim Al BakirGastroenterology Department, Chelsea and Westminster Hospital, London, UK.
Anjan DharDepartment of Gastroenterology, Darlington Memorial Hospital, Darlington, Durham, UK.ORCID http://orcid.org/0000-0001-8964-2031
Sunil DolwaniDivision of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Omar FaizDepartment of Surgery and Cancer, Imperial College London, London, UK.
Ailsa HartDepartment of Gastroenterology, St Mark's Hospital and Academic Institute, London, UK.
Bu'Hussain HayeeKing's Health Partners Institute for Therapeutic Endoscopy, King's College Hospital NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0003-1670-8815
Chris HealeyDepartment of Gastroenterology, Airedale NHS Foundation Trust, Keighley, West Yorkshire, UK.
Simon John LeedhamTranslational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Marco R NovelliDepartment of Histopathology, University College London, London, UK.
Tim RaineDepartment of Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Matthew D RutterDepartment of Gastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK.ORCID http://orcid.org/0000-0001-9507-0295
Neil A ShepherdGloucestershire Cellular Pathology Laboratory, Cheltenham General Hospital, Cheltenham, Gloucestershire, UK.
Venkataraman SubramanianDepartment of Gastroenterology, St James's University Hospital, Leeds, UK.
Margaret VanceDepartment of Gastroenterology, St Mark's Hospital and Academic Institute, London, UK.
Ruth WakemanCrohn's and Colitis UK, Hatfield, UK.
Lydia WhiteTranslational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Nigel J TrudgillDepartment of Gastroenterology, Sandwell and West Birmingham NHS Trust, West Bromwich, UK.ORCID http://orcid.org/0000-0002-8040-8158
A John MorrisDepartment of Gastroenterology, Glasgow Royal Infirmary, Glasgow, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with inflammatory bowel disease (IBD) remain at increased risk for colorectal cancer and death from colorectal cancer compared with the general population despite improvements in inflammation control with advanced therapies, colonoscopic surveillance and reductions in environmental risk factors. This guideline update from 2010 for colorectal surveillance of patients over 16 years with colonic inflammatory bowel disease was developed by stakeholders representing UK physicians, endoscopists, surgeons, specialist nurses and patients with GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodological support.An a priori protocol was published describing the approach to three levels of statement: GRADE recommendations, good practice statements or expert opinion statements. A systematic review of 7599 publications, with appraisal and GRADE analysis of trials and network meta-analysis, where appropriate, was performed. Risk thresholding guided GRADE judgements.We made 73 statements for the delivery of an IBD colorectal surveillance service, including outcome standards for service and endoscopist audit, and the importance of shared decision-making with patients.Core areas include: risk of colorectal cancer, IBD-related post-colonoscopy colorectal cancer; service organisation and supporting patient concordance; starting and stopping surveillance, who should or should not receive surveillance; risk stratification, including web-based multivariate risk calculation of surveillance intervals; colonoscopic modalities, bowel preparation, biomarkers and artificial intelligence aided detection; chemoprevention; the role of non-conventional dysplasia, serrated lesions and non-targeted biopsies; management of dysplasia, both endoscopic and surgical, and the structure and role of the multidisciplinary team in IBD dysplasia management; training in IBD colonoscopic surveillance, sustainability (green endoscopy), cost-effectiveness and patient experience. Sixteen research priorities are suggested.

Indexed as

COLONOSCOPYCOLORECTAL CANCER SCREENINGCOLORECTAL NEOPLASIAENDOSCOPYIBD

Identifiers

PMID40306978
PMCPMC13018778

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.