Evidence map›Paper›PMID 40306930›Full record

ArticleJournal of neurointerventional surgery2026

Volume-outcome trends in ruptured intracranial aneurysm treatment: German healthcare data from 2013 to 2022.

Christian Haverkamp, Konstantinos Vagkopoulos, Klaus Kaier, Mukesch Johannes Shah, Constantin von Zur Mühlen, Jürgen Beck, Horst Urbach, Stephan Meckel

Abstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christian HaverkampInstitute of Digitalization in Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany christian.haverkamp@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0001-8165-4783
Konstantinos VagkopoulosDepartment of Neuroradiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Klaus KaierInstitute of Medical Biometry and Statistics, Department of Methods in Clinical Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Mukesch Johannes ShahDepartment of Neurosurgery, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-7224-9185
Constantin von Zur MühlenDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Jürgen BeckDepartment of Neurosurgery, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Horst UrbachDepartment of Neuroradiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Stephan MeckelDepartment of Neuroradiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-6468-4526

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubarachnoid hemorrhage (SAH) is a life-threatening condition with a high risk of disability requiring specialized care. This study investigated the relationship between hospital annual case volume and outcomes for patients undergoing clipping and endovascular treatment (EVT) of ruptured intracranial aneurysms (IAs) in Germany.

methodsGerman Federal Statistical Office data (2013-2022) derived from all German hospitals were analyzed for ruptured IA cases treated with EVT or clipping. Primary outcomes were in-hospital mortality and poor neurological outcome according to the National Inpatient Sample-SAH Outcome Measure. Poisson regression was used to assess the annual case volume-outcome relationship.

resultsIn 35 187 treatment cases for ruptured IA, a significant inverse relationship was found between annual case volume and both mortality and poor neurological outcomes for both treatment modalities. Each additional case performed annually decreased adverse outcome risk by 1%. EVT showed lower rates of poor neurological outcome (39.8% vs 49.8%, P<0.001), shorter hospital stays, less intensive care, and lower costs, but similar in-hospital mortality rates (18.5% vs 19.1%, P=0.127) compared with clipping. The in-hospital mortality rate for clipping increased in 2016-2018, 2021, and 2022 compared with the 2013 baseline, whereas it remained stable for EVT. Age was a significant predictor of mortality and poor neurological outcome.

conclusionsThis study is the first to quantify the volume-outcome relationship for treatment of ruptured IAs in Germany. Consistent results across treatment modalities suggest benefits of increased experience of neurovascular treatment centers. These findings enhance our understanding of factors influencing neurovascular care outcomes in Germany.

Indexed as

Aneurysm, RupturedEndovascular ProceduresIntracranial AneurysmSubarachnoid HemorrhageAdultAgedFemaleGermanyHospital MortalityHospitals, High-VolumeHumansMaleMiddle AgedTreatment OutcomeAneurysmCatheterCoilSubarachnoid Hemorrhage

Identifiers

PMID40306930
PMCPMC13217071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.