Evidence map›Paper›PMID 40306928›Full record

ArticleJournal of neurointerventional surgery2026

Higher risk of recurrence in partially thrombosed cerebral aneurysms post-WEB (Woven EndoBridge) device treatment: insights from the WorldWideWEB Consortium registry.

Guillaume Saliou, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Assala Aslan, Christian Swaid, Miguel Cuellar, Mahmoud Dibas, Nicole M Cancelliere, Jose Danilo Bengzon Diestro and 75 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurointerventional surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

85 authors.

Guillaume SaliouDiagnostic and Interventional Radiology, Lausanne University Hospital, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-3832-7976
Hamza Adel SalimNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0002-5208-8425
Basel MusmarDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, Louisiana, USA.ORCID http://orcid.org/0009-0000-4910-6090
Nimer AdeebDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, Louisiana, USA.
Assala AslanDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University System, Shreveport, Louisiana, USA.
Christian SwaidDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, Louisiana, USA.
Miguel CuellarDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, Louisiana, USA.
Mahmoud DibasDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, Louisiana, USA.ORCID http://orcid.org/0000-0003-1690-1084
Nicole M CancelliereNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St Michael's Hospital, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-8703-4304
Jose Danilo Bengzon DiestroNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St Michael's Hospital, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-8450-2021
Oktay AlginDepartment of Radiology, Ankara University Medical Faculty Ibn i Sina Hospital, Ankara, Turkey.
Sherief GhozyDepartments of Radiology and Neurosurgery, Mayo Clinic, Rochester, New York, USA.ORCID http://orcid.org/0000-0001-5629-3023
Sovann V LayDepartment of Neuroradiology, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.ORCID http://orcid.org/0000-0003-4105-0664
Adrien GuenegoDepartment of Neuroradiology, Hôpital Universitaire Erasme, Brussels, Belgium.ORCID http://orcid.org/0000-0001-7281-1652
Leonardo RenieriDepartment of Neuroradiology, Ospedale Careggi Di Firenze, Firenze, Italy.
Joseph Anthony CarnevaleDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, New York, USA.ORCID http://orcid.org/0000-0002-9477-9996
Panagiotis MastorakosDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Kareem ElNaamaniDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.ORCID http://orcid.org/0000-0001-5294-1003
Eimad ShotarDepartment of Neuroradiology, Hôpital de la Pitié-Salpêtrière, Paris, France.ORCID http://orcid.org/0000-0002-8712-8431
Markus A MöhlenbruchDepartment of Neuroradiology, UniversitätsKlinikum Heidelberg, Heidelberg, Germany.
Michael KralDepartment of Neurosurgery, Christian Doppler University Hospital & Institute of Neurointervention, Salzburg, Austria.
Charlotte ChungDepartments of Radiology & Neurosurgery, NYU Langone Health, New York, New York, USA.ORCID http://orcid.org/0000-0003-0671-4111
Mohamed M SalemDepartment of Neurosurgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.ORCID http://orcid.org/0000-0001-8483-2995
Ivan LylykDepartment of Neuroradiology, Clínica La Sagrada Familia, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-6048-4225
Paul M ForemanDepartment of Neurosurgery, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, Florida, USA.
Hamza ShaikhDepartment of Radiology & Neurosurgery, Cooper University Hospital, Camden, New Jersey, USA.ORCID http://orcid.org/0000-0001-8163-4600
Vedran ŽupančićDepartment of Radiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
Muhammad Ubaid HafeezDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Houston, Texas, USA.ORCID http://orcid.org/0000-0001-8631-4227
Joshua S CatapanoDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.ORCID http://orcid.org/0000-0001-6599-0269
Muhammad WaqasDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, New York, USA.
Muhammet ArslanDepartment of Radiology, Pamukkale University, Pamukkale, Turkey.
Onur ErgunDepartment of Radiology, Pamukkale University, Pamukkale, Turkey.
James D RabinovNeuroendovascular Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Yifan RenDepartment of Neuroradiology, Austin Health, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-6518-6828
Clemens M SchirmerDepartment of Neurosurgery and Radiology, Geisinger Hospital, Danville, Pennsylvania, USA.ORCID http://orcid.org/0000-0003-1743-8781
Mariangela PianoDepartment of Neuroradiology, Ospedale Niguarda Cà Granda, Milano, Italy.
Anna Luisa KuhnDepartment of Neuroradiology, UMass Memorial Hospital, Worcester, Massachusetts, USA.
Caterina MichelozziDepartment of Neuroradiology, Ospedale San Raffaele Sede di San Raffaele Turro, Milan, Italy.ORCID http://orcid.org/0000-0001-6339-448X
Robert M StarkeDepartment of Neurosurgery, University of Miami, Miami, Florida, USA.
Ameer E HassanDepartment of Neuroradiology, Valley Baptist Neuroscience Institute, Harlingen, Texas, USA.ORCID http://orcid.org/0000-0002-7148-7616
Mark OgilvieDepartments of Neurosurgery and Radiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID http://orcid.org/0000-0001-8226-762X
Anh NguyenDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-9343-8276
Jesse JonesDepartments of Neurosurgery and Radiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID http://orcid.org/0000-0002-2682-9736
Waleed BrinjikjiDepartments of Radiology and Neurosurgery, Mayo Clinic, Rochester, New York, USA.ORCID http://orcid.org/0000-0001-5271-5524
Marie Teresa NawkaDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-7423-9725
Marios-Nikos PsychogiosDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Basel, Basel, Switzerland.
Christian UlfertDepartment of Neuroradiology, UniversitätsKlinikum Heidelberg, Heidelberg, Germany.
Bryan PukenasDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA.
Jan Karl BurkhardtDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA.
Thien J HuynhDepartments of Radiology and Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA.
Juan Carlos Martinez-GutierrezDepartment of Neuroradiology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID http://orcid.org/0000-0002-6722-8267
Muhammed Amir EssibayiDepartment of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0001-8325-2382
Sunil A ShethDepartment of Neuroradiology, University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID http://orcid.org/0000-0003-0602-8509
Diana SlawskiDepartment of Radiology, Stanford University School of Medicine, Stanford, California, USA.
Rabih TawkNeurosurgery, Mayo Clinic Hospital Jacksonville, Jacksonville, Florida, USA.ORCID http://orcid.org/0000-0002-2695-0042
Benjamin PulliRadiology, Stanford University School of Medicine, Stanford, California, USA.ORCID http://orcid.org/0000-0002-1795-9897
Boris LubiczDepartment of Neuroradiology, Hôpital Universitaire Erasme, Bruxelles, Belgium.
Pietro PanniDepartment of Neuroradiology, Ospedale San Raffaele, Milano, Italy.
Ajit S PuriDepartment of Neuroradiology, UMass Memorial Hospital, Worcester, Massachusetts, USA.
Guglielmo PeroDepartment of Neuroradiology, Ospedale Niguarda Cà Granda, Milano, Italy.ORCID http://orcid.org/0000-0002-8932-6909
Eytan RazDepartments of Radiology & Neurosurgery, NYU Langone Health Center, New York, New York, USA.ORCID http://orcid.org/0000-0003-2998-8481
Christoph J GriessenauerDepartment of Neurosurgery, Christian Doppler University Hospital & Institute of Neurointervention, Salzburg, Austria.ORCID http://orcid.org/0000-0002-2952-3812
Hamed AsadiDepartments of Radiology & Neurosurgery, NYU Langone Health Center, Dublin, Ireland.
Adnan H SiddiquiDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, New York, USA.ORCID http://orcid.org/0000-0002-9519-0059
Elad I LevyDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, New York, USA.ORCID http://orcid.org/0000-0002-6208-3724
Neil HaranhalliDepartment of Neurosurgery, Montefiore Medical Center, New York, New York, USA.
David AltschulDepartment of Neurosurgery, Montefiore Medical Center, New York, New York, USA.
Andrew F DucruetDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.
Felipe C AlbuquerqueDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.ORCID http://orcid.org/0000-0003-3251-1086
Robert W RegenhardtNeuroendovascular Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Christopher J StapletonMassachusetts General Hospital, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0003-4805-0093
Peter KanDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Galveston, Texas, USA.ORCID http://orcid.org/0000-0001-6649-4128
Vladimir KalousekDepartment of Neuroradiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.ORCID http://orcid.org/0000-0002-1439-0930
Pedro LylykDepartment of Neuroradiology, Clínica La Sagrada Familia, Buenos Aires, Argentina.
Srikanth Reddy BodduDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, New York, USA.
Jared KnopmanDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, New York, USA.
Stavropoula I TjoumakarisDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.ORCID http://orcid.org/0000-0002-1054-9414
Hugo CuellarDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, Louisiana, USA.ORCID http://orcid.org/0000-0002-8348-4535
Pascal JabbourDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.ORCID http://orcid.org/0000-0002-1544-4910
Frédéric ClarençonDepartment of Neuroradiology, Hôpital Pitié-Salpêtrière, Paris, France.
Nicola LimbucciDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, New York, USA.
Vitor M PereiraNeurovascular Centre, St Michael's Hospital, Toronto, Ontario, Canada.
Aman B PatelNeuroendovascular Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Adam A DmytriwNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0003-0131-5699
Steven D HajduDiagnostic and Interventional Radiology, Lausanne University Hospital, Lausanne, Switzerland Steven.hajdu@chuv.ch.ORCID http://orcid.org/0000-0001-7659-4325

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Woven EndoBridge (WEB) device is a prevalent treatment for intracranial aneurysms. While many studies have assessed the obliteration rate post-WEB embolization, few have focused on long-term outcomes in partially thrombosed aneurysms.

objectiveTo assess whether partially thrombosed aneurysms are at higher risk of recurrence or retreatment following WEB embolization compared with non-thrombosed aneurysms.

methodsWe evaluated data from 22 academic institutions, focusing on previously untreated cerebral aneurysms treated with the WEB device. Logistic regression was utilized to analyze factors predicting long-term aneurysm obliteration and retreatment necessity.

resultsAmong 1303 patients, 26 presented with a partially thrombosed aneurysm. In the partially thrombosed group, the mean aneurysm maximal diameter was 10.7±4 mm with a neck ratio of 1.99±1.19 mm, larger than in the control group where the mean aneurysm maximal diameter was 6.81±2.37 mm with a neck ratio of 1.64±0.51 mm (P<0.001 for both maximal diameter and neck ratio). At the final follow-up, partially thrombosed aneurysms treated by the WEB device had a 38.5% retreatment rate, compared with 7.0% for non-thrombosed aneurysms (P<0.001). Among partially thrombosed aneurysms, the Raymond-Roy type IIIa/b occlusion rate was higher (38.5% vs 9.9%, P<0.001). On multivariate analysis, partially thrombosed aneurysms compared with non-thrombosed aneurysms had an increased rate of retreatment (OR 3.64, 95% CI 1.28 to 10.1).

conclusionPartially thrombosed aneurysms are associated with a poorer occlusion rate and a higher rate of retreatment following WEB embolization. For partially thrombosed aneurysms, the WEB device appears suboptimal as a first-line treatment, and therefore alternative techniques should be prioritized.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmIntracranial ThrombosisRegistriesAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsTreatment OutcomeAneurysmCoilHemorrhageSubarachnoid

Identifiers

PMID40306928
PMCPMC13217109

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