Evidence map›Paper›PMID 40305576›Full record

ArticleScience translational medicine2025

Objective autonomic signatures of tinnitus and sound sensitivity disorders.

Samuel S Smith, Kelly N Jahn, Jenna A Sugai, Kenneth E Hancock, Daniel B Polley

Abstract read
In one paragraph

Article in Science translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Tinnitus.Nature reviews. Disease primers · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samuel S SmithEaton-Peabody Laboratories, Massachusetts Eye and Ear, Boston, MA 02114, USA.ORCID 0000-0003-0991-8224
Kelly N JahnEaton-Peabody Laboratories, Massachusetts Eye and Ear, Boston, MA 02114, USA.ORCID 0000-0002-5832-5137
Jenna A SugaiEaton-Peabody Laboratories, Massachusetts Eye and Ear, Boston, MA 02114, USA.ORCID 0000-0002-6145-4909
Kenneth E HancockEaton-Peabody Laboratories, Massachusetts Eye and Ear, Boston, MA 02114, USA.ORCID 0000-0002-5629-498X
Daniel B PolleyEaton-Peabody Laboratories, Massachusetts Eye and Ear, Boston, MA 02114, USA.ORCID 0000-0002-5120-2409

Funding

Synaptopathy, Neural Pathophysiology and Suprathreshold Processing in Gerbils with Normal or Elevated ThresholdsP50DC015857 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Daniel B. Polley · 2017 to 2026
$28.1M
Neural Signatures of Enhanced Central Auditory Gain in HyperacusisK01DC019647 · NIDCD · UNIVERSITY OF TEXAS DALLAS · PI JAHN, KELLY NICOLE · 2021 to 2023
$415k
NIDCD NIH HHS K01 DC019647NIDCD NIH HHS P50 DC015857
6 · The paper itself

Abstract

Hypersensitivity, phantom percepts, and sensory reactivity are core features of many neurological disorders. Direct, objective measurements of these features have proven difficult to identify, leaving subjective questionnaires as the primary means of assessing sensory disorder severity. Here, we studied neurotypical adults (

Indexed as

Autonomic Nervous SystemHyperacusisSoundTinnitusAcoustic StimulationAdultFemaleHumansMaleMiddle AgedSurveys and Questionnaires

Identifiers

PMID40305576
PMCPMC12340780

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.