Evidence map›Paper›PMID 40305512›Full record

ArticleAnnals of medicine2025

Role of endoscopic ultrasound as a predictor of histological healing in ulcerative colitis.

Jin Tian, Wei Wang, Yongshuai Liu, Xin Zhang, Hanqing Zhao, Hongmei Qu

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Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jin TianSchool of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.ORCID 0009-0001-6397-6612
Wei WangDepartment of Gastroenterology, the First Affiliated Hospital of Shandong Second Medical University, Weifang People's Hospital, Weifang, Shandong, China.
Yongshuai LiuDepartment of Gastroenterology, the First Affiliated Hospital of Shandong Second Medical University, Weifang People's Hospital, Weifang, Shandong, China.
Xin ZhangSchool of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.
Hanqing ZhaoSchool of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.
Hongmei QuDepartment of Gastroenterology, the First Affiliated Hospital of Shandong Second Medical University, Weifang People's Hospital, Weifang, Shandong, China.ORCID 0009-0003-2117-2928

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUlcerative colitis (UC) is a chronic inflammatory bowel disease with rising global prevalence.Histological healing (HH) is a key treatment target associated with better long-term outcomes. Although endoscopic ultrasound (EUS) is known to be related to both clinical and endoscopic activity in UC, its role in defining HH remains unclear. Therefore, this study was aimed at investigating the association between EUS and histological activity (HA), as well as the predictive potential of EUS for HH.

methodIn this cross-sectional analysis, 68 UC adults underwent EUS and colonoscopy with biopsies. We used the Mayo Endoscopic Score (MES) for endoscopic activity, the Nancy Index (NI) for biopsy grading, and the Endoscopic Ultrasound-Ulcerative Colitis (EUS-UC) score for EUS analysis, defining endoscopic remission as MES ≤ 1 and HH as NI ≤ 1.A receiver operating characteristic (ROC) curve was employed to evaluate the ability of the indices to predict HH.

resultsTotally 23 patients (33.80%) achieved HH, while 45 (66.20%) showed HA. The EUS-UC scores were significantly lower in the HH group (

conclusionThe EUS-UC score has a significant correlation with histological outcomes and shows strong potential as a reliable, invasive predictor of HH in UC, with implications for improved disease monitoring.

Indexed as

Colitis, UlcerativeEndosonographyAdultAgedBiopsyColonColonoscopyCross-Sectional StudiesFemaleHumansMaleMiddle AgedPredictive Value of TestsROC CurveSeverity of Illness IndexWound HealingEndoscopic ultrasoundhistological healingMayo endoscopic scorepredictive valueulcerative colitis

Identifiers

PMID40305512
PMCPMC12044909

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.