SynthesisWomen's health (London, England)
Effect of balanced protein-energy supplementation given to pregnant women on birth outcomes: A systematic review and meta-analysis.
Synthesis in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Impact of a Prenatal Nutrition Package with Balanced Energy Supplementation on Gestational Weight Gain in Amhara, Ethiopia.The Journal of nutrition · 2026Trial
- Effects of Nutritional Interventions During Pregnancy on Maternal and Neonatal Outcomes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2026Review
- Factors associated with birth weight and birth length among term newborns in Vietnam: a retrospective cross-sectional study.Child health nursing research · 2026Article
- Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is an increased demand for nutrition during pregnancy to improve fetal growth and development. Several dietary interventions have been recommended to pregnant women to meet their maternal needs. Using a larger sample size, we aim to assess the effect of balanced protein-energy supplementation given to pregnant women on birth outcomes.
objectiveTo evaluate the effect of balanced protein-energy supplementation given to pregnant women on birth outcomes.
designSearch included PubMed, Cochrane Central, and Embase from initiation till 20 March 2023 to select relevant studies examining perinatal factors associated with balanced protein-energy supplementation. Mean differences (MD) and risk ratios (RRs) with a 95% confidence interval (CI) were calculated using Review Manager. DATA SOURCES AND
methodsRandomized controlled trials and observational studies were included. Out of 218,720 studies initially identified, 24 met the inclusion criteria, involving pregnant women who received balanced protein-energy supplementation and reported outcomes related to perinatal death, birthweight, length, or head circumference.
resultsMeta-analysis of pooled studies revealed that balanced protein supplementation had a significant effect on birthweight (g) (MD: 62.67, CI: 27.92-97.43), low birth weight (LBW) (RR: 0.73, CI: 0.57-0.95), birth length (MD: 0.20, CI: 0.10-0.30), and small-for-gestational-age (SGA) babies (RR: 0.74, CI: 0.59-0.93) and had no significant effect on the birth head circumference (MD: 0.05, CI: -0.09 to 0.20), perinatal death (RR: 0.83, CI: 0.50-1.37), and preterm birth (RR: 0.86, CI: 0.68-1.08).
conclusionBalanced protein-energy supplementation is an effective intervention for birth length, birth weight, risk of LBW, and SGA births, particularly in women who are undernourished.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.