Evidence map›Paper›PMID 40305435›Full record

ArticlePLOS global public health2025

Comparing lagged impacts of mobility changes and environmental factors on COVID-19 waves in rural and urban India: A Bayesian spatiotemporal modelling study.

Eimear Cleary, Fatumah Atuhaire, Alessandro Sorichetta, Nick Ruktanonchai, Cori Ruktanonchai, Alexander Cunningham, Massimiliano Pasqui, Marcello Schiavina, Michele Melchiorri, Maksym Bondarenko and 6 more

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Eimear ClearyWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0003-2549-8565
Fatumah AtuhaireWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
Alessandro SorichettaDepartment of Earth Sciences "Ardito Desio", Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-3576-5826
Nick RuktanonchaiDepartment of Population Health Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, United States of America.
Cori RuktanonchaiDepartment of Population Health Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, United States of America.
Alexander CunninghamWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
Massimiliano PasquiInstitute for Bioeconomy, National Research Council of Italy (IBE-CNR), Rome, Italy.ORCID https://orcid.org/0000-0002-0926-362X
Marcello SchiavinaEuropean Commission, Joint Research Centre, Ispra, Virginia, Italy.ORCID https://orcid.org/0000-0003-3399-3400
Michele MelchiorriEuropean Commission, Joint Research Centre, Ispra, Virginia, Italy.ORCID https://orcid.org/0000-0002-3009-8868
Maksym BondarenkoWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
Harry E R ShepherdWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0002-7077-3581
Sabu S PadmadasDepartment of Social Statistics & Demography, Faculty of Social Sciences, University of Southampton, Southampton, United Kingdom.
Amy WesolowskiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Derek A T CummingsDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Andrew J TatemWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
Shengjie LaiWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0001-9781-8148

Funding

Human mobility models to forecast disease dynamics and the effectiveness of public health interventionsR01AI160780 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CUMMINGS, DEREK A, WESOLOWSKI, AMY · 2021 to 2025
$3.3M
Gates Foundation INV-024911NIAID NIH HHS R01 AI160780
6 · The paper itself

Abstract

Previous research in India has identified urbanisation, human mobility and population demographics as key variables associated with higher district level COVID-19 incidence. However, the spatiotemporal dynamics of mobility patterns in rural and urban areas in India, in conjunction with other drivers of COVID-19 transmission, have not been fully investigated. We explored travel networks within India during two pandemic waves using aggregated and anonymized weekly human movement datasets obtained from Google, and quantified changes in mobility before and during the pandemic compared with the mean baseline mobility for the 8-week time period at the beginning of 2020. We fit Bayesian spatiotemporal hierarchical models coupled with distributed lag non-linear models (DLNM) within the integrated nested Laplace approximation (INLA) package in R to examine the lag-response associations of drivers of COVID-19 transmission in urban, suburban and rural districts in India during two pandemic waves in 2020-2021. Model results demonstrate that recovery of mobility to 99% that of pre-pandemic levels was associated with an increase in relative risk of COVID-19 transmission during the Delta wave of transmission. This increased mobility, coupled with reduced stringency in public intervention policy and the emergence of the Delta variant, were the main contributors to the high COVID-19 transmission peak in India in April 2021. During both pandemic waves in India, reduction in human mobility, higher stringency of interventions, and climate factors (temperature and precipitation) had 2-week lag-response impacts on the [Formula: see text] of COVID-19 transmission, with variations in drivers of COVID-19 transmission observed across urban, rural and suburban areas. With the increased likelihood of emergent novel infections and disease outbreaks under a changing global climate, providing a framework for understanding the lagged impact of spatiotemporal drivers of infection transmission will be crucial for informing interventions.

Identifiers

PMID40305435
PMCPMC12043145

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.