ArticleBiomolecules2025
The Quantification of Vitamin D in Humans: A Promising, Non-Invasive and Cost-Effective Method to Measure 25-Hydroxyvitamin D.
Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Lab-in-a-Droplet: Utilizing Acoustic Levitation for Miniaturized Sample Preparation and LC-MS/MS, Exemplified by Measurement of Vitamin D in Serum.Analytical chemistry · 2026Article
- Updated perspectives on vitamin D deficiency, screening, supplementation and clinical guidance.Cardiovascular diabetology. Endocrinology reports · 2026Review
- Multifactor machine learning models for predicting urinary tract infections: a pilot study.International urology and nephrology · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundVitamin D intake and synthesis are essential. Vitamin D deficiency is increasing across all age groups, raising concerns regarding public health. Serum 25(OH)D is measured to define vitamin D deficiency. However, its quantification in non-invasively collected biological matrices is still poorly studied. This study aimed to assess 25(OH)D levels in unconventional matrices using cost-effective analytical methods.
methodsSerum, urine, and saliva were collected from 62 healthy, non-smoking volunteers, 25-44 years of age. Biological samples were analysed using the Enzyme-Linked Immunosorbent Assay (ELISA). The serum was additionally analysed via the chemiluminescent microparticle immunoassay (CMIA), which was used as a benchmark.
resultsWe observed a linear correlation (Pearson r = 0.44;
conclusionOur study opens up the possibility of using urinary 25(OH)D levels as a proxy measurement of vitamin D. Such an approach may allow future investigations on the association between environmental factors and vitamin D assessed in non-invasively collected biological matrices via cost-effective analytical methods.
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Registered trials
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