Evidence map›Paper›PMID 40305338›Full record

ArticleBiomolecules2025

Association of Lower COMT Activity Alleles with Aggressive Traits in Male Youth with Conduct Disorder Living in a Correctional Facility.

Lucija Tudor, Josip Podobnik, Gordana Nedic Erjavec, Matea Nikolac Perkovic, Jaanus Harro, Margus Kanarik, Darko Marcinko, Dubravka Svob Strac, Melita Cusek, Vlatka Kovac and 1 more

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lucija TudorRudjer Boskovic Institute, Division of Molecular Medicine, 10000 Zagreb, Croatia.ORCID 0000-0002-9125-406X
Josip PodobnikDepartment of Psychiatry, Psychiatric Hospital for Children and Youth Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-9997-3707
Gordana Nedic ErjavecRudjer Boskovic Institute, Division of Molecular Medicine, 10000 Zagreb, Croatia.ORCID 0000-0002-0787-9340
Matea Nikolac PerkovicRudjer Boskovic Institute, Division of Molecular Medicine, 10000 Zagreb, Croatia.ORCID 0000-0002-3113-0778
Jaanus HarroNeuropsychopharmacology, Institute of Chemistry, University of Tartu, 50411 Tartu, Estonia.ORCID 0000-0002-4484-2096
Margus KanarikNeuropsychopharmacology, Institute of Chemistry, University of Tartu, 50411 Tartu, Estonia.ORCID 0000-0002-3326-5297
Darko MarcinkoDepartment of Psychiatry, Clinical Hospital Center Zagreb, 10000 Zagreb, Croatia.
Dubravka Svob StracRudjer Boskovic Institute, Division of Molecular Medicine, 10000 Zagreb, Croatia.ORCID 0000-0001-6200-2405
Melita CusekJuvenile Correctional Facility Ivanec, 42240 Ivanec, Croatia.
Vlatka KovacDepartment for Child and Adolescent Psychiatry, Clinical Hospital Center Osijek, 31000 Osijek, Croatia.
Nela PivacRudjer Boskovic Institute, Division of Molecular Medicine, 10000 Zagreb, Croatia.

Funding

Estonian Research Council PRG1213Ministry of Sciences, Education and Sports of the Republic of Croatia 098-0982522-2455
6 · The paper itself

Abstract

Aggression constitutes a significant behavioral issue associated with delinquent behavior, commonly observed in youth diagnosed with conduct disorder (CD) and living in correctional facilities. Catechol-o-methyl-transferase

Indexed as

AggressionCatechol O-MethyltransferaseConduct DisorderAdolescentAllelesCorrectional FacilitiesGenetic Predisposition to DiseaseGenotypeHaplotypesHumansMalePolymorphism, Single NucleotideCatechol O-MethyltransferaseCOMT protein, humanaggressionassociationCOMT rs4680 and rs4818 polymorphismsconduct disordercorrectional facilitygenetic variantsmale youth

Identifiers

PMID40305338
PMCPMC12024663

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.