Evidence map›Paper›PMID 40305297›Full record

ReviewBiomolecules2025

Bone Modelling and Remodelling in Cold Environment.

Leyi Xue, Qiao Guan, Lingli Zhang

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Combined polysaccharides fromFrontiers in microbiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leyi XueCollege of Athletic Performance, Shanghai University of Sport, Shanghai 200438, China.ORCID 0009-0008-4195-419X
Qiao GuanSchool of Exercise and Health, Shanghai University of Sport, Shanghai 200438, China.ORCID 0009-0006-4231-3285
Lingli ZhangCollege of Athletic Performance, Shanghai University of Sport, Shanghai 200438, China.ORCID 0000-0003-3832-4046

Funding

National Natural Science Foundation of China 82272608Shanghai Key Laboratory of Human Performance (Shanghai University of sport) 11DZ2261100
6 · The paper itself

Abstract

People engaged in various activities in cold environments-such as those living in cold climates, polar workers, cold storage workers, and athletes engaged in winter sports-are frequently affected by cold environments. Therefore, it is of great significance to explore the modelling and remodelling of bones in cold environments. Cold environments can shorten the length of bones, thin the thickness of bones, decrease bone mineral density (BMD), change the biomechanical properties of bones, and lead to bone loss. In addition, cold directly affects the bone microenvironment. Exposure to cold causes spindle-like and fibroblast-like changes in bone marrow mesenchymal stem cells (BMSCs) and decreases their proliferation, and cold exposure promotes the osteogenic differentiation of BMSCs partly through the

Indexed as

Bone and BonesBone RemodelingCold TemperatureAnimalsBone DensityCell DifferentiationHumansMesenchymal Stem CellsOsteogenesisbonebone fatbone microenvironmentbone vascularitycold environment

Identifiers

PMID40305297
PMCPMC12025219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.