Evidence map›Paper›PMID 40305283›Full record

ArticleBiomolecules2025

A pH-Responsive Dendritic-DNA-Based Nanohydrogel for Dual Drug Delivery.

Jing Zhao, Jingyuan Wu, Yiqi Fan, Chao Yu, Le Yu, Fangwei Shao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing ZhaoDepartment of Chemistry, Zhejiang University, Hangzhou 310000, China.ORCID 0000-0003-2596-7536
Jingyuan WuDivision of Chemistry and Biological Chemistry, Nanyang Technological University, Singapore 639956, Singapore.
Yiqi FanDepartment of Chemistry, Zhejiang University, Hangzhou 310000, China.
Chao YuDepartment of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310000, China.
Le YuDepartment of Chemistry, Zhejiang University, Hangzhou 310000, China.
Fangwei ShaoNational Key Laboratory of Biobased Transportation Fuel Technology, Zhejiang University-University of Illinois, Urbana-Champaign Institute, Zhejiang University, Haining 314400, China.ORCID 0000-0003-2007-3920

Funding

the National Natural Science Foundation of China 21975217
6 · The paper itself

Abstract

The rational design of multifunctional drug delivery systems capable of achieving precise drug release remains a huge challenge. Herein, we designed a stimuli-responsive dendritic-DNA-based nanohydrogel as a nanocarrier to achieve the co-delivery of doxorubicin and

Indexed as

DendrimersDNADoxorubicinDrug Delivery SystemsHydrogelsNanoparticlesCell Line, TumorDrug CarriersDrug LiberationHumansHydrogen-Ion ConcentrationOligonucleotides, AntisenseTumor MicroenvironmentDendrimersDNADoxorubicinDrug CarriersHydrogelsOligonucleotides, Antisensechemotherapydual treatmentsgene silencingnanohydrogelsstimulus-responsive nanomaterialstargeted delivery

Identifiers

PMID40305283
PMCPMC12024947

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.