ArticleBiomolecules2025
The Frequency of a Magnetic Field Reduces the Viability and Proliferation of Numerous Tumor Cell Lines.
Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
The frequency of a magnetic field has led to the development of physicochemical interaction models and to the consideration of the role of frequency as a fundamental parameter in the change of cell behavior. The main objective of this article is to find a frequency window to decrease the viability and proliferation of different tumor cell lines to compare the frequency response of each. For this purpose, tumor cell lines PC12 (rat), B16F10 (mouse), SKBR3 (human), MDA-MB-231 (human), and the non-tumor cell line 3T3 (mouse) are exposed to a magnetic field of 100 µT for 24, 48, and 72 hours in frequency windows contained in the range [20-100] Hz, and their viability and proliferation behavior is evaluated. The results show a frequency-, exposure-time-, and cell-line-dependent behavior, with the most pronounced changes for most cell lines at frequencies of 45, 50, and 55 Hz. It is concluded that each cell type could respond to specific frequency codes that allow the modification of its behavior in vital cellular processes related to tumor development. Knowledge of these codes would allow for the therapeutic application of magnetic fields in oncological pathologies.
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