Evidence map›Paper›PMID 40305199›Full record

ArticleBiomolecules2025

Platelet-Sourced TGF-β Promotes Th17 Responses and Enhances Airway Neutrophilia.

Ruoning Wang, Dandan Wu, Chunqing Wang, Amanda Livingston, Xiang Wu, Meilian Liu, Xuexian O Yang

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruoning WangDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.ORCID 0000-0002-9716-3089
Dandan WuDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.ORCID 0000-0003-2073-5998
Chunqing WangDepartment of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.ORCID 0000-0002-2811-7230
Amanda LivingstonDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
Xiang WuDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
Meilian LiuDepartment of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.ORCID 0000-0003-1639-262X
Xuexian O YangDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.ORCID 0000-0001-6816-7024

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
UNM TRAININGP50GM085273 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI WANDINGER-NESS, ANGELA · 2009 to 2018
$26.1M
Unfolded Protein Response and Autophagy in T Helper Cell Effector FunctionP20GM121176 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Samuel Joseph Endicott · 2017 to 2026
$24.9M
The Cytokine Suppressor CIS in Giant Cell PneumonitisR01HL148337 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI YANG, XUEXIAN · 2020 to 2023
$1.5M
Control of the Survival Pathways in TH17 CellsR21AI187912 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Xuexian Yang · 2025 to 2026
$413k
NCI NIH HHS P30 CA118100NHLBI NIH HHS R01 HL148337NIAID NIH HHS R21 AI187912NIGMS NIH HHS P20 GM121176NIGMS NIH HHS P50 GM085273NIH HHS AI142200NIH HHS HL148337
6 · The paper itself

Abstract

Microbial, especially fungal, sensitization has been associated with the development and exacerbation of treatment-refractory neutrophilic asthma. Among the airway-inhabiting fungi,

Indexed as

AsthmaBlood PlateletsNeutrophilsTh17 CellsTransforming Growth Factor betaAnimalsCandida albicansHumansLungMiceMice, Inbred C57BLTransforming Growth Factor betaasthmaCandida albicansplateletTGF-βTH17

Identifiers

PMID40305199
PMCPMC12024734

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.