Evidence map›Paper›PMID 40305139›Full record

ArticleChemistry, an Asian journal2025

Non-Symmetrical Tetradentate Mixed Halogen Bonding-Hydrogen Bonding Macrocycles for Anion Recognition in Aqueous-Organic Media.

Somjutar Opascharoenboon, Sutthipoj Vigromsitdet, Norraset Cheevathanomsak, Inkarat Atirojwanich, Jonggol Tantirungrotechai, Mongkol Sukwattanasinitt, Panida Surawatanawong, Paul D Beer, Thanthapatra Bunchuay

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry, an Asian journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Somjutar OpascharoenboonDepartment of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Rd, Thung Phayathai, Ratchathewi, Bangkok, 10400, Thailand.
Sutthipoj VigromsitdetDepartment of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Rd, Thung Phayathai, Ratchathewi, Bangkok, 10400, Thailand.
Norraset CheevathanomsakDepartment of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Rd, Thung Phayathai, Ratchathewi, Bangkok, 10400, Thailand.
Inkarat AtirojwanichDepartment of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Rd, Thung Phayathai, Ratchathewi, Bangkok, 10400, Thailand.
Jonggol TantirungrotechaiDepartment of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Rd, Thung Phayathai, Ratchathewi, Bangkok, 10400, Thailand.
Mongkol SukwattanasinittDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Phyathai Road, Wangmai, Pathumwan, Bangkok, 10330, Thailand.
Panida SurawatanawongDepartment of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Rd, Thung Phayathai, Ratchathewi, Bangkok, 10400, Thailand.
Paul D BeerChemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Rd, Oxford, OX1 3TA, UK.
Thanthapatra BunchuayDepartment of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Rd, Thung Phayathai, Ratchathewi, Bangkok, 10400, Thailand.ORCID https://orcid.org/0000-0001-5665-0254

Funding

National Research Council of Thailand N42A661000Office of the Permanent Secretary, Ministry of Higher Education, Science, Research and Innovation, Thailand RGNS 65 -150
6 · The paper itself

Abstract

The prevalence of anions in biological systems, the environment, and industrial processes has driven the development of synthetic receptors capable of their selective recognition and detection. As a result of high hydration energy, the diversity in shape, and the pH-dependent nature of anions, such receptors require a highly preorganized binding site decorated with complementary multiple noncovalent interactions to stabilize anion-receptor complexation. In this study, a series of charge-neutral tetradentate macrocycles with non-symmetrical structures containing both halogen bonding (XB) iodotriazole and hydrogen bonding (HB) triazole donors were prepared via a stepwise CuAAC macrocyclization reaction. The non-symmetrical XB/HB macrocycles displayed increased anion binding affinities and contrasting anion selectivities in comparison to a symmetrical all HB macrocycle analogue, even in the presence of water, but still exhibited halide binding less strongly than the analogous all XB macrocycle. As a result of the macrocyclic effect and the number and nature of donor groups, the non-symmetrical XB/HB macrocycles exhibited the largest enhancement of Cl

Indexed as

AnionHalogen bondingHydrogen bondingMacrocyclesSupramolecular chemistry

Identifiers

PMID40305139
PMCPMC12182393

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.