Evidence map›Paper›PMID 40305082›Full record

ArticleeLife2025

Interpreting roles of mutations associated with the emergence of

Saugat Poudel, Jason Hyun, Ying Hefner, Jon Monk, Victor Nizet, Bernhard O Palsson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saugat PoudelUniversity of California, San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0002-3732-2463
Jason HyunUniversity of California, San Diego, La Jolla, United States.
Ying HefnerUniversity of California, San Diego, La Jolla, United States.
Jon MonkPalmona Pathogenomics, Menlo Park, United States.
Victor NizetCollaborative to Halt Antibiotic-Resistant Microbes (CHARM), Department of Pediatrics, University of California San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0003-3847-0422
Bernhard O PalssonUniversity of California, San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0003-2357-6785

Funding

Systems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host ImmunityU01AI124316 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 2016 to 2020
$10.2M
National Institute of Allergy and Infectious Diseases AI124316NIAID NIH HHS U01 AI124316
6 · The paper itself

Abstract

The

Indexed as

Gene Expression Regulation, BacterialGene Regulatory NetworksMethicillin-Resistant Staphylococcus aureusMutationStaphylococcal InfectionsStaphylococcus aureusGenome-Wide Association StudyHumanscomputational biologyGWASindependent component analysisinfectious diseasemicrobiologyStaphylococcus aureussystems biologytranscriptional regulatory network

Identifiers

PMID40305082
PMCPMC12043316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.