ArticleProceedings of the National Academy of Sciences of the United States of America2025
The expanded immunoregulatory protease network in mosquitoes is governed by gene coexpression.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Partial reconstitution of the prophenoloxidase activation system inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- The effects of dietary iron supplementation on bacterial infections inbioRxiv : the preprint server for biology · 2026Article
- The effects of dietary iron supplementation on bacterial infections in Manduca sexta larval hemolymph.PloS one · 2026Article
- Distinct roles of theCurrent research in insect science · 2026Article
- Gut bacteria induce heterologous immune priming in Rhodnius prolixus encompassing both humoral and cellular immune responses.PLoS pathogens · 2025Article
- Article
- CLIPA protein pairs function as cofactors for prophenoloxidase activation in Anopheles gambiae.Insect biochemistry and molecular biology · 2025Article
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2 authors.
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Abstract
Serine protease cascades regulate key innate immune responses. Their activation cleaves a series of inactive protease zymogens, which then activate downstream effector enzymes, ensuring a rapid response. In mosquitoes, these cascades involve clip-domain serine proteases and their noncatalytic homologs (CLIPs), whose make-up and structural organization are not fully understood. Here, we systematically assessed the contribution of individual CLIPs to humoral immunity in
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