Observational studyJournal of immigrant and minority health2025
A Single-Center Report of Hypertension in Native American Kidney Transplant Recipients.
Observational study in Journal of immigrant and minority health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Based on the current American Heart Association/American College of Cardiology definition [systolic blood pressure (SBP) ≥ 130 and/or diastolic BP(DBP) ≥ 80], hypertension affects 45% of the adult U.S. population. Post-kidney transplant (KT) hypertension has been associated with immunosuppression and worse graft outcomes. Hypertension data on Native American (NAm) KT recipients (KTR) is scarce. In our center, we serve a significant NAm population, and measure ambulatory blood pressure (AMBP) routinely in KTR at 4- and 12-months post-transplant. In a noninterventional, observational study we queried our transplant database for all NAm KTR who were transplanted at our center between years 2003 and 2023. Patients who had 4- and/or 12-months AMBP were included in our study. 262 NAm KTR met inclusion criteria. Average (sd) BP was 133.0 (15.0)/76.2 (9.7) and 134.1 (15.6)/76.5 (9.9) at 4- and 12-months respectively. Male gender (p = 0.03) and older donor age (p = 0.02) were associated with BP ≥ 130/80 at 4-months. Male gender (p = 0.05) and pre-transplant diabetes (p = 0.01) were associated with BP ≥ 130/80 at 12-months. About two-thirds of NAm KTR had uncontrolled hypertension at 4- and 12-months. The burden of hypertension, as measured by the gold standard AMBP monitoring is significant in NAm KTR, and therefore, attention to hypertension management is prudent in this minority patient population.
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