Evidence map›Paper›PMID 40304911›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Quantifying the Electrophysiological Properties of Cells Using Dielectrophoresis.

Krista S P Clarke, Oreoluwa V Griffiths, Kai Hoettges, Rebecca Lewis, Fatima H Labeed

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Krista S P ClarkeCentre for Biomedical Engineering, School of Mechanical Engineering Sciences, University of Surrey, Guildford, Surrey, UK.
Oreoluwa V GriffithsCentre for Biomedical Engineering, School of Mechanical Engineering Sciences, University of Surrey, Guildford, Surrey, UK.
Kai HoettgesDepartment of Electrical Engineering and Electronics, University of Liverpool, Liverpool, UK.
Rebecca LewisDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, University of Surrey, Guildford, Surrey, UK.
Fatima H LabeedDepartment of Biology, United Arab Emirates University, Al Ain, UAE. f.labeed@uaeu.ac.ae.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 3DEP Reader (DEPtech) is a commercial noninvasive, high throughput, easily adoptable benchtop microfluidic platform that utilizes the principles of dielectrophoresis to analyze cells in suspension and determine their electrical properties. This protocol describes the operation, value, and common setup of the platform to provide users with the ability to characterize three important electrophysiological parameters of approximately 20,000 cells in under 2 min. Dielectrophoresis (DEP) is an electrokinetic phenomenon which describes the movement of suspended polarizable cells, in a nonuniform electric field. The 3DEP plots the relative DEP force experienced by cells across a range of AC frequencies generating a spectrum through which membrane conductance, membrane capacitance, and cytoplasmic conductivity are derived.

Indexed as

ElectrophoresisElectrophysiological PhenomenaMicrofluidic Analytical TechniquesAnimalsElectric ConductivityHumans3DEPCytoplasmic conductivity (σcyto)Dielectrophoresis (DEP)Effective membrane capacitance (Ceff)Effective membrane conductance (Geff)Electric field (EF)Potassium ion (K+)Sodium ion (Na+)Weight per volume (w/v)

Identifiers

PMID40304911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.