Evidence map›Paper›PMID 40304821›Full record

SynthesisAging clinical and experimental research2025

Comparative effectiveness of different dual task mode interventions on cognitive function in older adults with mild cognitive impairment or dementia: a systematic review and network meta-analysis.

Yuqing Hao, Yajie Zhao, Huanhuan Luo, Lanying Xie, Huixiu Hu, Chao Sun

Abstract readComparative StudyNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuqing Hao *Department of Nursing, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, No. 1 Da Hua Road, DongDan, Beijing, 100730, People's Republic of China.ORCID http://orcid.org/0009-0005-5096-1779
Yajie Zhao *Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, Beijing, People's Republic of China.
Huanhuan LuoDepartment of Nursing, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, No. 1 Da Hua Road, DongDan, Beijing, 100730, People's Republic of China.
Lanying XieSchool of Nursing, Beijing University of Traditional Chinese Medicine, Beijing, People's Republic of China.
Huixiu HuDepartment of Nursing, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, No. 1 Da Hua Road, DongDan, Beijing, 100730, People's Republic of China. 18610145247@163.com.
Chao SunDepartment of Nursing, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, No. 1 Da Hua Road, DongDan, Beijing, 100730, People's Republic of China. sunchaobjyy@163.com.

Funding

Fundamental Research Funds for the Central Universities 3332023093the Central High-level Hospital Clinical Research Operating Expenses Special Medical-industrial Integration Special Program BJ-2024-167the National Natural Science Foundation of China 72304046the National Natural Science Foundation of China 72474032
6 · The paper itself

Abstract

objectivesTo evaluate and compare the effects of different dual task interventions on cognitive function in older adults with cognitive impairment or dementia.

methodsWe searched eight databases, including PubMed, Cochrane Library, and EMBASE, to obtain studies exclusively comprising randomized controlled trials on dual task interventions in individuals aged 60 and older with mild cognitive impairment or dementia, up to July 28, 2024. Study quality was evaluated using the Cochrane Risk of Bias Tool. Analyses included pairwise meta-analyses via Review Manager 5.4 and network meta-analyses via Stata 14.0.

resultsA total of 32 RCTs involving 2370 participants were included. Dual cognitive task training had the most significant impact on global cognition (SUCRA = 79.2%, mean rank = 1.6) and motor-cognitive dual task training was the only dual task intervention with a notable improvement in executive function (SMD = 1.53, 95% CI 0.06-3.01). For physical function, dual motor task training was most effective, improving gait performance (SMD = 0.34), muscle strength (SMD = 0.28), and balance (SMD = 0.90). Motor-cognitive dual task training demonstrated the greatest effectiveness in enhancing activities of daily living (SMD = 1.50) and quality of life (SMD = 1.20), while reducing depressive symptoms (SMD = - 0.96).

conclusionsDual cognitive task training is the most effective dual task intervention for enhancing global cognition. Motor-cognitive dual task training is the only dual task mode that significantly improves executive cognition.

Indexed as

CognitionCognitive DysfunctionDementiaActivities of Daily LivingAgedAged, 80 and overExecutive FunctionHumansMiddle AgedRandomized Controlled Trials as TopicCognitive functionCombined interventionsDementiaDual taskMild cognitive impairmentNetwork meta-analysis

Identifiers

PMID40304821
PMCPMC12043736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.