Evidence map›Paper›PMID 40304784›Full record

ArticleInternational urogynecology journal2025

Preoperative Analgesia in Midurethral Sling: A Cohort Study.

Marcus Ortega, Mireya Taboada, Elizabeth Dotson, Kaitlyn James, Alexa Silfen, Youngwu Kim-Ortega, Milena Weinstein, Dan Ellis

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Article in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcus OrtegaDepartment of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. mortega7@mgh.harvard.edu.ORCID 0000-0001-8310-5665
Mireya TaboadaDepartment of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Elizabeth DotsonDepartment of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Kaitlyn JamesDeborah Kelly Center for Outcomes Research, Massachusetts General Hospital, Boston, MA, USA.
Alexa SilfenDeborah Kelly Center for Outcomes Research, Massachusetts General Hospital, Boston, MA, USA.
Youngwu Kim-OrtegaDepartment of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Milena WeinsteinDepartment of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Dan EllisDepartment of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisStress urinary incontinence (SUI) is a common condition among adult women in the USA, with its prevalence expected to rise owing to an aging population. Midurethral sling (MUS) procedures are a well-established surgical treatment for SUI. Enhanced Recovery After Surgery (ERAS) protocols advocate for multimodal pain management strategies, including preoperative analgesia. However, limited data exist on the effectiveness of preoperative pain medications in MUS procedures. This study examines the impact of preoperative analgesia on postoperative pain scores and opioid consumption.

methodsA retrospective cohort study analyzed women who underwent MUS placement between 2018 and 2022 within a New England health care system. Patients were stratified by preoperative pain medication use. Primary outcomes included postoperative pain scores and opioid consumption. Secondary outcomes assessed anesthesia type, sling type, and operative time. Multivariable regression analyses adjusted for confounders.

resultsA total of 631 patients met the inclusion criteria, with 400 receiving preoperative pain medications. Patients with preoperative analgesia had significantly lower median postoperative pain scores (p = 0.013) and were more likely to achieve acceptable pain control (p = 0.014). However, adjusted analyses found no significant difference in opioid consumption or pain scores between groups.

conclusionPreoperative pain medications were associated with improved pain scores in unadjusted analyses but did not demonstrate independent statistical significance after adjusting for confounders. These findings highlight the complexity of pain management in MUS procedures. Further randomized studies are needed to refine ERAS pain strategies in urogynecological surgery.

Indexed as

AnalgesiaPain ManagementPostoperative PainPreoperative CareSuburethral SlingsUrinary Incontinence, StressAdultAgedAnalgesics, OpioidCohort StudiesFemaleHumansMiddle AgedPain MeasurementRetrospective StudiesAnalgesics, OpioidEnhanced recoveryMidurethral slingOutcomesPain controlStress incontinence

Identifiers

PMID40304784

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.