Evidence map›Paper›PMID 40304756›Full record

ReviewRheumatology international2025

Anti-TIF1-beta autoantibody-positive dermatomyositis: a case-based review.

Jean-Baptiste Vulsteke, Petra De Haes, Minoru Satoh, Ben Van Cleynenbreugel, Benoit Beuselinck, Xavier Bossuyt, Ellen De Langhe

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Rheumatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jean-Baptiste VulstekeUniversity Hospitals Leuven, Rheumatology, Leuven, Belgium. jean-baptiste.vulsteke@uzleuven.be.ORCID http://orcid.org/0000-0001-5753-2794
Petra De HaesKU Leuven, Microbiology, Immunology and Transplantation, Leuven, Belgium.
Minoru SatohKitakyushu Yahata-Higashi Hospital, Department of Medicine, Kitakyushu, Japan.
Ben Van CleynenbreugelKU Leuven, Development and Regeneration, Urogenital, Abdominal and Plastic Surgery, Leuven, Belgium.
Benoit BeuselinckKU Leuven, Oncology, Laboratory of Experimental Oncology, Leuven, Belgium.
Xavier BossuytKU Leuven, Microbiology, Immunology and Transplantation, Clinical and Diagnostic Immunology, Leuven, Belgium.
Ellen De LangheUniversity Hospitals Leuven, Rheumatology, Leuven, Belgium.

Funding

Fonds Wetenschappelijk Onderzoek Fonds Wetenschappelijk Onderzoek
6 · The paper itself

Abstract

To describe the clinical features and cancer risk in patients with dermatomyositis (DM) and anti-TIF1β autoantibodies without other DM-specific autoantibodies (anti-TIF1β-monospecific DM) through a case-based review. Case report of anti-TIF1β-monospecific cancer-associated DM and literature review of cases of anti-TIF1β-monospecific DM. We describe a case of a person with cancer-associated DM in whom we identified anti-TIF1β autoantibodies through immunoprecipitation-mass spectrometry. He had typical cutaneous involvement, mild myositis and a good response to medical therapy after curative treatment of an underlying renal cell cancer. A literature search of Pubmed and Scopus identified 9 more persons with anti-TIF1β-monospecific DM revealing a homogeneous phenotype with typical cutaneous involvement, mild to absent muscular involvement and absence of interstitial lung disease. Two out of ten (20%) had cancer-associated DM. Anti-TIF1β-monospecific DM represents a homogeneous subset of DM characterized by typical cutaneous involvement, mild to absent myositis and potentially an elevated cancer risk (20%). More cohort studies with adequate detection methods are needed to formally assess the cancer risk as compared to anti-TIF1γ and other DM-specific autoantibodies.

Indexed as

AutoantibodiesCarcinoma, Renal CellDermatomyositisKidney NeoplasmsTranscription FactorsHumansMaleMiddle AgedAutoantibodiesTranscription FactorsTRIM33 protein, humanAutoantibodiesDermatomyositisIdiopathic inflammatory myopathyMyositis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.