ArticleHuman molecular genetics2025
Driving Global Health equity and precision medicine through African genomic data.
Article in Human molecular genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Neuropsychiatry genetics in Africa.Nature communications · 2026Review
- Advancing risk gene discovery across the allele frequency spectrum.HGG advances · 2026Review
- Multi-ancestry modeling improves fine-mapping resolution, protein prediction, and discovery for proteome-wide association studies.medRxiv : the preprint server for health sciences · 2026Article
- Insights into the genetic aetiology of diabetes in Africa.EBioMedicine · 2026Review
- Identification of key genes as diagnostic biomarkers for lung adenocarcinoma using bioinformatics and machine learning.Discover oncology · 2026Article
- Unlocking Ethiopia's genomic landscape and its global significance: a call for inclusive genomics research.Human genomics · 2026Review
- An evolutionary genomic perspective on preterm birth, genome editing, and pregnancy in the human species.Frontiers in genome editing · 2026Review
- Article
- Engaging migrants and immigrants in genetics research.Nature genetics · 2025Review
- KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease.Nature genetics · 2025Article
- Ancestry gaps in cardiovascular GWAS: a multi-database review of African representation in genomic studies.Frontiers in genetics · 2025Review
- Next generation sequencing in dilated cardiomyopathy: utility and challenges in the African context.Frontiers in cardiovascular medicine · 2025Review
- Africa's Place in Precision Medicine: Implications for Global Health Equity and Health Systems.Health equityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Significant gaps persist despite the progress in raising awareness of genomic diversity and including individuals of African ancestry in genomic research. African populations remain underrepresented in genomic studies despite their deep evolutionary history, demographic diversity, and unique genetic architecture for gene discovery. This underrepresentation constrains the portability of findings from other populations to African settings due to the poor predictive performance of genetic scores. Consequently, it hinders global efforts in translational research, slows the progression of genomic medicine, and worsens health disparities-a missed opportunity for precision medicine globally. However, genuine prioritisation and expansion of genomic data collection from individuals of African ancestry can drive more equitable health solutions that benefit all populations. In this review, we highlight the opportunities presented by African genomic diversity, the urgent need for larger datasets and biobanks with diverse phenotypes from African populations, and recent developments in African genomic research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.