Evidence map›Paper›PMID 40304582›Full record

ReviewRadiology. Artificial intelligence2025

The Evolution of Radiology Image Annotation in the Era of Large Language Models.

Adam E Flanders, Xindi Wang, Carol C Wu, Felipe C Kitamura, George Shih, John Mongan, Yifan Peng

Abstract readReview
In one paragraph

Review in Radiology. Artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam E FlandersDepartment of Radiology, Thomas Jefferson University, 132 S Tenth St, Ste 1080 B Main Building, Philadelphia, PA 19107.ORCID 0000-0002-4679-0787
Xindi WangDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY.ORCID 0000-0002-6548-3547
Carol C WuDepartment of Thoracic Imaging, The University of Texas MD Anderson Cancer Center, Houston, Tex.ORCID 0000-0003-1005-0995
Felipe C KitamuraDepartment of Diagnostic Imaging, Universidade Federal de São Paulo, São Paulo, Brazil.ORCID 0000-0002-9992-5630
George ShihDepartment of Radiology, Weill Cornell Medical College, New York, NY.ORCID 0000-0002-8356-2011
John MonganDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif.ORCID 0000-0003-2765-7451
Yifan PengDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY.ORCID 0000-0001-9309-8331

Funding

MEDICAL IMAGING AND DATA RESOURCE CENTER (MIDRC) YEAR 375N92020D00021 · NIBIB · UNIVERSITY OF CHICAGO · PI GIGER, MARYELLEN · 2021 to 2025
$16.6M
Multimodal AI Fusion Model for Early Detection for Pancreatic CancerR01CA289249 · NCI · MAYO CLINIC ARIZONA · PI Imon Banerjee, Yifan Peng · 2024 to 2026
$2.8M
NCI NIH HHS R01 CA289249NHLBI NIH HHS 75N92020D00021
6 · The paper itself

Abstract

Although there are relatively few diverse, high-quality medical imaging datasets on which to train computer vision artificial intelligence models, even fewer datasets contain expertly classified observations that can be repurposed to train or test such models. The traditional annotation process is laborious and time-consuming. Repurposing annotations and consolidating similar types of annotations from disparate sources has never been practical. Until recently, the use of natural language processing to convert a clinical radiology report into labels required custom training of a language model for each use case. Newer technologies such as large language models have made it possible to generate accurate and normalized labels at scale, using only clinical reports and specific prompt engineering. The combination of automatically generated labels extracted and normalized from reports in conjunction with foundational image models provides a means to create labels for model training. This article provides a short history and review of the annotation and labeling process of medical images, from the traditional manual methods to the newest semiautomated methods that provide a more scalable solution for creating useful models more efficiently.

Indexed as

Artificial IntelligenceData CurationNatural Language ProcessingRadiologyRadiology Information SystemsHumansLarge Language ModelsDiagnosisFeature DetectionSemi-supervised Learning

Identifiers

PMID40304582
PMCPMC12319696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.