Evidence map›Paper›PMID 40304318›Full record

ReviewCurrent topics in medicinal chemistry2025

Current Organoid Culture Systems in Pancreatic Cancer.

Lei Liu, Jing Sun, Sheng Chen, Xuechan Tang, Shuai Zhang, Min Wang, Qian Yue, Changqing Zhong, Lianyong Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lei LiuDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.ORCID 0009-0005-0463-2886
Jing SunSpinal Surgery, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.ORCID 0009-0002-6647-4738
Sheng ChenDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.
Xuechan TangDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.
Shuai ZhangDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.
Min WangDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.
Qian YueDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.
Changqing ZhongDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.
Lianyong LiDepartment of Gastroenterology, The Ninth Medical Center of Chinese PLA General Hospital, Beijing 100101, China.ORCID 0000-0002-0852-7005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite advances in therapeutic regimens, Pancreatic Cancer (PC) still remains an aggressive malignancy characterized by high treatment resistance, mortality, and poor clinical outcome. Hence, there is an urgent need for more effective therapeutic methods to improve the survival of PC patients. Currently, organoid culture systems have emerged as a preclinical research model for studying cancer progression, biology, and treatment responses, bridging the translational gap between

Indexed as

OrganoidsPancreatic NeoplasmsAnimalsCell Culture TechniquesHumansCRISPR-Cas9MatrigelorganoidsPancreatic cancerpatient-derived tumor xenograftsPluripotent stem cells

Identifiers

PMID40304318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.