Evidence map›Paper›PMID 40304315›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2025

Childhood trauma, adolescent risk behaviours and cardiovascular health indices in the 2004 Pelotas Birth Cohort.

Megan Bailey, Graeme Fairchild, Gemma Hammerton, Ina S Santos, Luciana Tovo-Rodrigues, Joseph Murray, Alicia Matijasevich, Sarah L Halligan

Abstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Megan BaileyDepartment of Psychology, University of Bath, Bath, UK.ORCID 0000-0003-4372-1775
Graeme FairchildDepartment of Psychology, University of Bath, Bath, UK.ORCID 0000-0001-7814-9938
Gemma HammertonCentre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0002-7781-3857
Ina S SantosPost-Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
Luciana Tovo-RodriguesPost-Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0002-8732-6059
Joseph MurrayPost-Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0002-5511-3454
Alicia MatijasevichPost-Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0003-0060-1589
Sarah L HalliganDepartment of Psychology, University of Bath, Bath, UK.ORCID 0000-0002-3436-3358

Funding

All for Health InstituteBrazilian Ministry of HealthBrazilian National Research Council 303042/2018-4Brazilian National Research Council 308319/2021-4Brazilian National Research Council 312746/2021-0Brazilian National Research Council 409224/2021-9Children's PastorateEconomic and Social Research Council ES/P000630/1Economic and Social Research Council ES/Z503599/1L'Oréal-Unesco-ABC Program for Women in Science in Brazil-2020National Support Program for Centers of ExcellenceResearch Support Foundation of the State of Rio Grande do SulResearch Support Foundation of the State of São Paulo 2014/13864-6Research Support Foundation of the State of São Paulo 2020/07730-8Research Support Foundation of the State of São Paulo 2023/12905-0Wellcome TrustWorld Health Organization
6 · The paper itself

Abstract

backgroundChildhood trauma has been associated with increased risk of substance use and poor sleep, with these factors linked to subsequent poor cardiovascular health. However, there has been little longitudinal research exploring these associations in adolescence, especially in low- and middle-income countries (LMICs). To address this, we investigated longitudinal pathways from trauma to risk behaviours and cardiovascular health indices among adolescents in the 2004 Pelotas Birth Cohort, Brazil.

methodsLifetime cumulative trauma was assessed via caregiver reports up to age 11, and combined adolescent/caregiver reports at ages 15 and 18. At age 18, current problematic alcohol use, smoking, illicit drug use and sleep duration were measured via self-report and resting heart rate (HR) and blood pressure (BP) were assessed. We tested for trauma risk behaviour-HR/BP associations using multivariable regression, population attributable fractions and counterfactual mediation.

resultsOf 4,229 adolescents (51.9% boys), 81.9% were trauma-exposed by age 18. Cumulative trauma up to ages 15 and 18 increased the odds of age 18 alcohol, smoking and drug use (adjusted ORs: 1.25-1.44). Sleep duration was unrelated to childhood trauma. Population attributable fractions indicated that childhood trauma explained ≥28% of age 18 substance use. Unexpectedly, greater trauma exposure was associated with lower resting HR and BP. Substance use partially mediated the effect of trauma on cardiovascular health indices.

conclusionsTrauma is associated with substance use in LMIC adolescents. Prevention and intervention strategies targeting trauma are critical given this significant burden. Our finding that trauma predicts lower HR/BP warrants further exploration given well-established associations between trauma and poorer cardiovascular health in adulthood.

Indexed as

Adolescent BehaviorAdverse Childhood ExperiencesBlood PressureCardiovascular DiseasesHeart RatePsychological TraumaRisk-TakingSleep Wake DisordersSmokingSubstance-Related DisordersAdolescentBirth CohortBrazilChildFemaleHumansadolescentChildhood traumapsychophysiologyrisk behaviourssubstance use

Identifiers

PMID40304315
PMCPMC12571934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.