Evidence map›Paper›PMID 40304112›Full record

ArticleJournal of cosmetic dermatology2025

Dynamic Periocular Wrinkle Patterns: An Anatomical Study on Young Adults.

Istemihan Coban, Fulya Yaprak Erkmen, Gülsüm Derya Aktaş

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Istemihan CobanDepartment of Anatomy, Faculty of Medicine, Izmir Democracy University, Izmir, Turkey.ORCID https://orcid.org/0000-0001-7104-2118
Fulya Yaprak ErkmenDepartment of Anatomy, Faculty of Medicine, Izmir Democracy University, Izmir, Turkey.ORCID https://orcid.org/0000-0001-5597-9461
Gülsüm Derya AktaşDepartment of Anatomy, Faculty of Medicine, Izmir Democracy University, Izmir, Turkey.ORCID https://orcid.org/0000-0002-3098-2098

Funding

Scientific Research Projects Board of Izmir Democracy University 294
6 · The paper itself

Abstract

backgroundAging causes facial wrinkles, especially dynamic wrinkles related to mimic movements, predisposing areas to static wrinkles from a young age, notably in the periorbital region. This study aims to analyze dynamic wrinkle patterns on periorbital skin during mimic movements in healthy young adults to identify wrinkle precursor regions.

methodsDynamic periorbital wrinkle patterns were analyzed in 184 healthy adults (93 females, 91 males) aged 18-24 years. Standardized facial photographs were taken at rest and during various mimic movements. The periorbital region was divided into superior, inferior, lateral, and medial subregions; wrinkle patterns were classified and analyzed. Interobserver and intraobserver reliability were assessed.

resultsIn the upper periorbital region, the most common wrinkle pattern was oblique lines extending from the medial and lateral canthus to the upper corners (Type 3, 56%). Inferiorly, the most common pattern was a linear wave from the lateral canthus to the lateral margin (Type 3, 25.5%). Medially, no specific pattern (Type 6, 33.2%) and an arrowhead-like motif directed toward the medial canthus (Type 2, 20.7%) were prevalent. Laterally, radial waves extending from the lateral canthus to the lateral brow tip were most common (Type 1, 34.8%). The absence of a distinct wrinkle pattern in the medial region was more common in men than in women (48.4% vs. 17.6%). Males were more likely to have wrinkle patterns consisting of oblique short lines in the inferolateral direction in the inferior region (Type 2, 31.2%). Miniature crow's feet-like wrinkles were more common in females.

conclusionThis study presents a new classification of dynamic wrinkle patterns in the periorbital region in young adults, highlighting sex differences.

Indexed as

FaceSkin AgingAdolescentAdultEyelidsFemaleHealthy VolunteersHumansMaleObserver VariationPhotographyReproducibility of ResultsYoung Adultanatomyeyelidsfacial expressionfacial musclesskin agingwrinkles

Identifiers

PMID40304112
PMCPMC12042157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.