Evidence map›Paper›PMID 40303899›Full record

ArticlePain reports2025

Beyond coincidence: a case series on the clinical course of coinciding cluster headache and short-lasting unilateral neuralgiform headache attacks.

Julia J Jansen, Job Scheurink, Tijmen Balvers, Rolf Fronczek, Wim M Mulleners

Abstract read
In one paragraph

Article in Pain reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia J JansenDepartment of Neurology, Canisius-Wilhelmina Ziekenhuis, Nijmegen, the Netherlands.ORCID https://orcid.org/0009-0004-4420-7764
Job ScheurinkRadboud University Medical Center, Nijmegen, the Netherlands.
Tijmen BalversDepartment of Epilepsy, Stichting Epilepsie Instellingen Nederland (SEIN), Heemstede, the Netherlands.
Rolf FronczekDepartment of Neurology, Leiden University Medical Center, Leiden, the Netherlands.
Wim M MullenersThe Migraine Clinic, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Limited research has been conducted on co-occurring cluster headache and short-lasting unilateral neuralgiform headache attacks (SUNHA). Objectives: This case series aims to explore whether the observed overlap of cluster headache and SUNHA reflects a coincidental co-occurrence or suggests a shared underlying mechanism while also providing insights to improve diagnosis and management of these patients. Methods: A retrospective case series of 10 patients with a diagnosis of both cluster headache and SUNHA. Results: Two patients exhibited simultaneous onset of cluster headache and SUNHA ( Conclusion: This study constitutes the most extensive description to date of individuals diagnosed with both cluster headache and SUNHA. The observed co-occurrence of these headache types could suggest a pathophysiological relationship between the 2, which might be explained by a bidirectional interaction between posterior hypothalamic function and trigeminal root demyelination. The role of a trigeminal neurovascular conflict seems likely in this context, with dedicated magnetic resonance imaging being the optimal method for its identification. The potential role of microvascular decompression as a treatment in cluster-SUNHA cases where such a conflict is identified warrants further investigation.

Indexed as

Case seriesCluster headacheMicrovascular decompressionSUNASUNCTSUNHA

Identifiers

PMID40303899
PMCPMC12040040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.