Evidence map›Paper›PMID 40303835›Full record

ArticleJBMR plus2025

Obese-diabetic female

Gustavo A Gomez, Sasidhar Uppuganti, Sheila Pourteymoor, Jillian Bray, Jeffry S Nyman, Subburaman Mohan

Abstract read
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gustavo A GomezUS Department of Veterans Affairs, Loma Linda Healthcare System, Loma Linda, CA 92357, United States.
Sasidhar UppugantiDepartment of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, United States.
Sheila PourteymoorUS Department of Veterans Affairs, Loma Linda Healthcare System, Loma Linda, CA 92357, United States.
Jillian BrayUS Department of Veterans Affairs, Loma Linda Healthcare System, Loma Linda, CA 92357, United States.
Jeffry S NymanDepartment of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, United States.
Subburaman MohanUS Department of Veterans Affairs, Loma Linda Healthcare System, Loma Linda, CA 92357, United States.

Funding

Transgenic Approaches to Evaluate IGF-I Role in Peak BMDR01AR048139 · NIAMS · LOMA LINDA VETERANS ASSN RESEARCH &EDUC · PI MOHAN, SUBBURAMAN · 2003 to 2025
$4.7M
The Roles of Collagen and Water in the Fracture Resistance of BoneR01AR063157 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NYMAN, JEFFRY STEPHEN · 2012 to 2025
$3.9M
Thyroid hormone receptor β1 agonist therapy for the treatment of bone marrow adiposity in aging and obesityR21AG062866 · NIA · LOMA LINDA VETERANS ASSN RESEARCH & EDUC · PI MOHAN, SUBBURAMAN · 2020 to 2021
$403k
BLRD VA I01 BX005263BLRD VA IK6 BX005381BLRD VA IK6 BX007117NIAMS NIH HHS R01 AR048139NIAMS NIH HHS R01 AR063157NIA NIH HHS R21 AG062866
6 · The paper itself

Abstract

The influence of obesity and type 2 diabetes (T2D) on the skeleton is complex, with affected individuals having higher fracture risk despite having higher BMD. To evaluate how obesity and T2D affect skeletal health, we studied mice with disruption of a gene that regulates energy intake and expenditure,

Indexed as

bone material propertiesbone qualitybonesmouse modelsobesitytype 2 diabetes

Identifiers

PMID40303835
PMCPMC12035690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.