Evidence map›Paper›PMID 40303816›Full record

ReviewTransboundary and emerging diseases2023

Advances in CRISPR/Cas-Based Strategies on Zoonosis.

Yi Zhang, Qifeng Peng, Renjun Zhang, Chao Li, Quangang Xu, Luming Xia, Youming Wang, Ping Liu, Hong Pan

Abstract readReview
In one paragraph

Review in Transboundary and emerging diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yi ZhangInstitute of Zoonosis, College of Public Health, Zunyi Medical University, Zunyi, China.ORCID https://orcid.org/0000-0003-2883-0690
Qifeng PengInstitute of Zoonosis, College of Public Health, Zunyi Medical University, Zunyi, China.
Renjun ZhangCenter for Animal Disease Control and Prevention of Guizhou Province, Guiyang, China.
Chao LiChina Animal Health and Epidemiology Center, Qingdao, China.
Quangang XuChina Animal Health and Epidemiology Center, Qingdao, China.
Luming XiaCenter for Animal Disease Control and Prevention of Shanghai City, Shanghai, China.
Youming WangChina Animal Health and Epidemiology Center, Qingdao, China.
Ping LiuChina Animal Health and Epidemiology Center, Qingdao, China.
Hong PanInstitute of Zoonosis, College of Public Health, Zunyi Medical University, Zunyi, China.ORCID https://orcid.org/0000-0002-5603-9903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) has emerged as the predominant technique for gene editing technique due to its high efficiency and low cost. In the area of zoonosis, CRISPR/Cas is also widely used in different research areas. This paper reviewed the principles of CRISPR/Cas technique and its applications in zoonosis. Moreover, we analyze the shortcomings and weaknesses that currently limit its use, highlight its direction for improvement, and foresee its application prospects in the prevention and treatment of zoonosis. For the purpose of preventing and controlling zoonosis, we need to develop diagnostic method with high sensitivity and specificity, highly protective vaccines, and also better understanding of the pathogenesis. Our review aimed to promote the application and improvement of CRISPR/Cas technique in the above-mentioned areas, and provide brief and comprehensive references for CRISPR/Cas-based research. Through reviewing the advances in CRISPR/Cas-based strategies on zoonosis, we believe that CRISPR/Cas technique will provide more powerful assistance for the prevention and control of zoonosis.

Indexed as

CRISPR-Cas SystemsGene EditingZoonosesAnimalsClustered Regularly Interspaced Short Palindromic RepeatsHumans

Identifiers

PMID40303816
PMCPMC12017210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.